Immunology Antibodies 3
Anti-LY86 Antibody (CAB17051)
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- SKU:
- CAB17051
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-LY86 Antibody |
| Antibody SKU: | CAB17051 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human LY86 (NP_004262.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Jurkat, LO2, U-87MG |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human LY86 (NP_004262.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DFGF SVEK CSKQ LKSN INIR FGII LRED IKEL FLDL ALMS QGSS VLNF SYPI CEAA LPKF SFCG RRKG EQIY YAGP VNNP EFTI PQGE YQVL LELY TEKR S |
| Gene ID: | 9450 |
| Uniprot: | O95711 |
| Cellular Location: | Secreted, extracellular space |
| Calculated MW: | 17kDa |
| Observed MW: | 18kDa |
 | Western blot - LY86 Rabbit pAb (CAB17051) |
| Synonyms: | LY86, MD-1, MD1, MMD-1, dJ80N2.1 |
| Background: |
| UniProt Protein Function: | LY86: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Apoptosis Chromosomal Location of Human Ortholog: 6p25.1 Cellular Component: plasma membrane Biological Process: apoptosis; cell proliferation; humoral immune response; positive regulation of lipopolysaccharide-mediated signaling pathway |
| UniProt Code: | O95711 |
| NCBI GenInfo Identifier: | 20138465 |
| NCBI Gene ID: | 9450 |
| NCBI Accession: | O95711.1 |
| UniProt Secondary Accession: | O95711,Q9UQC4, |
| UniProt Related Accession: | O95711 |
| Molecular Weight: | 17,906 Da |
| NCBI Full Name: | Lymphocyte antigen 86 |
| NCBI Synonym Full Names: | lymphocyte antigen 86 |
| NCBI Official Symbol: | LY86 |
| NCBI Official Synonym Symbols: | MD1; MD-1; MMD-1; dJ80N2.1 |
| NCBI Protein Information: | lymphocyte antigen 86 |
| UniProt Protein Name: | Lymphocyte antigen 86 |
| UniProt Synonym Protein Names: | Protein MD-1 |
| Protein Family: | Lymphocyte antigen |
| UniProt Gene Name: | LY86 |
| UniProt Entry Name: | LY86_HUMAN |
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