Name: Anti-LY6E Antibody (CAB10225)
Brand: Cell Biology Antibodies 1
SKU: CAB10225
Availability: OutOfStock

Antibody Name:	Anti-LY6E Antibody
Antibody SKU:	CAB10225
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 21-101 of human LY6E (NP_002337.1).

Application:	WB IF
Recommended Dilution:	WB 1:1000 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse
Positive Samples:	LO2, 293T, SKOV3, MCF7, U-87MG, Mouse brain, Mouse kidney, Mouse liver

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 21-101 of human LY6E (NP_002337.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	LMCF SCLN QKSN LYCL KPTI CSDQ DNYC VTVS ASAG IGNL VTFG HSLS KTCS PACP IPEG VNVG VASM GISC CQSF LCNF S
Gene ID:	4061
Uniprot:	Q16553
Cellular Location:	Cell membrane, GPI-anchor, Lipid-anchor
Calculated MW:	13kDa
Observed MW:	14kDa

Synonyms:	LY6E, RIG-E, RIGE, SCA-2, SCA2, TSA-1
Background:

UniProt Protein Function:	LY6E: Induced by retinoic acid; in promyelocytic leukemia NB4 and in myeloblast HL-60 cell lines. Activated by IFN-alpha in monocytic cell line U-937 and in peripheral blood monocyte cells.
UniProt Protein Details:	Protein type:Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: integral to plasma membrane Biological Process: epinephrine secretion; organ growth; cell surface receptor linked signal transduction; in utero embryonic development; adrenal gland development; ventricular cardiac muscle morphogenesis; norepinephrine metabolic process
UniProt Code:	Q16553
NCBI GenInfo Identifier:	4505049
NCBI Gene ID:	4061
NCBI Accession:	NP_002337.1
UniProt Secondary Accession:	Q16553,Q0VDE5, B2R4X5, D3DWJ2,
UniProt Related Accession:	Q16553
Molecular Weight:	13,507 Da
NCBI Full Name:	lymphocyte antigen 6E
NCBI Synonym Full Names:	lymphocyte antigen 6 complex, locus E
NCBI Official Symbol:	LY6E
NCBI Official Synonym Symbols:	RIGE; SCA2; RIG-E; SCA-2; TSA-1
NCBI Protein Information:	lymphocyte antigen 6E
UniProt Protein Name:	Lymphocyte antigen 6E
UniProt Synonym Protein Names:	Retinoic acid-induced gene E protein; RIG-E; Stem cell antigen 2; SCA-2; Thymic shared antigen 1
Protein Family:	Lymphocyte antigen
UniProt Gene Name:	LY6E
UniProt Entry Name:	LY6E_HUMAN

	Western blot analysis of extracts of various cell lines, using LY6E antibody (CAB10225) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
	Immunofluorescence analysis of L929 cells using LY6E Rabbit pAb (CAB10225) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.