Cell Biology Antibodies 6

Anti-LTBP3 Antibody (CAB15687)

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SKU:
CAB15687
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-LTBP3 Antibody
Antibody SKU:CAB15687
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1004-1303 of human LTBP3 (NP_001123616.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:LO2, HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1004-1303 of human LTBP3 (NP_001123616.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ICKE GKCV NTQP GYEC YCKQ GFYY DGNL LECV DVDE CLDE SNCR NGVC ENTR GGYR CACT PPAE YSPA QRQC LSPE EMDV DECQ DPAA CRPG RCVN LPGS YRCE CRPP WVPG PSGR DCQL PESP AERA PERR DVCW SQRG EDGM CAGP LAGP ALTF DDCC CRQG RGWG AQCR PCPP RGAG SHCP TSQS ESNS FWDT SPLL LGKP PRDE DSSE EDSD ECRC VSGR CVPR PGGA VCEC PGGF QLDA SRAR CVDI DECR ELNQ RGLL CKSE RCVN TSGS FRCV CKAG FARS RPHG ACVP QRRR
Gene ID:4054
Uniprot:Q9NS15
Cellular Location:Secreted
Calculated MW:134kDa/139kDa
Observed MW:145kDa
Synonyms:LTBP3, DASS, LTBP-3, LTBP2, STHAG6, pp6425
Background:The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM).
NCBI Summary:The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
UniProt Code:Q9NS15
NCBI GenInfo Identifier:18466810
NCBI Gene ID:4054
NCBI Accession:AAF62352.3
UniProt Secondary Accession:Q9NS15,O15107, Q96HB9, Q9H7K2, Q9UFN4,
UniProt Related Accession:Q9NS15
Molecular Weight:134,292 Da
NCBI Full Name:latent transforming growth factor beta binding protein 3
NCBI Synonym Full Names:latent transforming growth factor beta binding protein 3
NCBI Official Symbol:LTBP3  
NCBI Official Synonym Symbols:DASS; LTBP2; LTBP-3; STHAG6; pp6425; GPHYSD3  
NCBI Protein Information:latent-transforming growth factor beta-binding protein 3
UniProt Protein Name:Latent-transforming growth factor beta-binding protein 3
Protein Family:Latent-transforming growth factor beta-binding protein
UniProt Gene Name:LTBP3  
Anti-LTBP3 Antibody (CAB15687)Western blot analysis of extracts of various cell lines, using LTBP3 antibody (CAB15687) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
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