Cell Biology Antibodies 6

Anti-LTB4R2 Antibody (CAB15479)

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SKU:
CAB15479
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-LTB4R2 Antibody
Antibody SKU:CAB15479
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 254-358 of human LTB4R2 (NP_062813.2).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 254-358 of human LTB4R2 (NP_062813.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PPEG ALAK LGGA GQAA RAGT TALA FFSS SVNP VLYV FTAG DLLP RAGP RFLT RLFE GSGE ARGG GRSR EGTM ELRT TPQL KVVG QGRG NGDP GGGM EKDG PEWD L
Gene ID:56413
Uniprot:Q9NPC1
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:37kDa/41kDa
Observed MW:43kDa
Synonyms:LTB4R2, BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9
Background:
UniProt Protein Function:LTB4R2: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: integral to plasma membrane; membrane; plasma membrane

Molecular Function:leukotriene B4 receptor activity; leukotriene receptor activity; peptide receptor activity, G-protein coupled

Biological Process: chemotaxis; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inflammatory response; negative regulation of adenylate cyclase activity; neuropeptide signaling pathway

UniProt Code:Q9NPC1
NCBI GenInfo Identifier:23821812
NCBI Gene ID:56413
NCBI Accession:Q9NPC1.1
UniProt Secondary Accession:Q9NPC1,Q5KU28, Q9NPE5,
UniProt Related Accession:Q9NPC1
Molecular Weight:37,942 Da
NCBI Full Name:Leukotriene B4 receptor 2
NCBI Synonym Full Names:leukotriene B4 receptor 2
NCBI Official Symbol:LTB4R2  
NCBI Official Synonym Symbols:BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2  
NCBI Protein Information:leukotriene B4 receptor 2
UniProt Protein Name:Leukotriene B4 receptor 2
UniProt Synonym Protein Names:LTB4 receptor JULF2; Leukotriene B4 receptor BLT2; Seven transmembrane receptor BLTR2
Protein Family:Leukotriene B4 receptor
UniProt Gene Name:LTB4R2  
UniProt Entry Name:LT4R2_HUMAN
Anti-LTB4R2 Antibody (CAB15479)Western blot analysis of extracts of various cell lines, using LTB4R2 antibody (CAB15479). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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