Cell Biology Antibodies 5
Anti-LTB4R Antibody (CAB15042)
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- SKU:
- CAB15042
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-LTB4R Antibody |
| Antibody SKU: | CAB15042 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human LTB4R (NP_858043.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse thymus |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human LTB4R (NP_858043.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SYSD IGRR LQAR RFRR SRRT GRLV VLII LTFA AFWL PYHV VNLA EAGR ALAG QAAG LGLV GKRL SLAR NVLI ALAF LSSS VNPV LYAC AGGG LLRS AGVG FVAK LLEG TGSE ASST RRGG SLGQ TARS GPAA LEPG PSES LTAS SPLK LNEL N |
| Gene ID: | 1241 |
| Uniprot: | Q15722 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 37kDa |
| Observed MW: | 37kDa |
| Synonyms: | LTB4R, BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7 |
| Background: |
| UniProt Protein Function: | LTB4R: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1 Chromosomal Location of Human Ortholog: 14q11.2-q12 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:leukotriene B4 receptor activity; nucleotide binding; leukotriene receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; muscle contraction; immune response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); cell motility; inflammatory response |
| UniProt Code: | Q15722 |
| NCBI GenInfo Identifier: | 221218998 |
| NCBI Gene ID: | 1241 |
| NCBI Accession: | NP_001137391.1 |
| UniProt Secondary Accession: | Q15722,Q13305, Q53XV5, Q92641, Q9BSU5, |
| UniProt Related Accession: | Q15722 |
| Molecular Weight: | 37,557 Da |
| NCBI Full Name: | leukotriene B4 receptor 1 |
| NCBI Synonym Full Names: | leukotriene B4 receptor |
| NCBI Official Symbol: | LTB4R |
| NCBI Official Synonym Symbols: | BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1 |
| NCBI Protein Information: | leukotriene B4 receptor 1; G protein-coupled receptor 16; G-protein coupled receptor 16; LTB4-R 1; LTB4-R1; P2Y purinoceptor 7; chemoattractant receptor-like 1; chemokine receptor-like 1; purinergic receptor P2Y, G-protein coupled, 7 |
| UniProt Protein Name: | Leukotriene B4 receptor 1 |
| UniProt Synonym Protein Names: | Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7 |
| Protein Family: | Multidrug-efflux transporter 2 regulator |
| UniProt Gene Name: | LTB4R |
| UniProt Entry Name: | LT4R1_HUMAN |
 | Western blot analysis of extracts of Mouse thymus, using LTB4R antibody (CAB15042) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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