Anti-LTB4R Antibody (CAB1315)
- SKU:
- CAB1315
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- LTB4R
- Synonyms:
- BLT1
- Synonyms:
- BLTR
- Synonyms:
- CMKRL1
- Synonyms:
- GPR16
- Synonyms:
- LTB4R1
- Synonyms:
- LTBR1
- Synonyms:
- P2RY7
- Synonyms:
- P2Y7
- Synonyms:
- leukotriene B4 receptor
- Research Area:
- Cell Biology
Description
| Product Name: | LTB4R Rabbit mAb |
| Product Code: | CAB1315 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | LTB4R, BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7, leukotriene B4 receptor |
| Applications: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human LTB4R. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse lung, Mouse liver, Rat lung, Rat liver |
| Immunogen: | A synthesized peptide derived from human LTB4R. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1241 |
| Uniprot: | Q15722 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 38kDa |
| Observed MW: | 38KDa |
| UniProt Protein Function: | LTB4R: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1 Chromosomal Location of Human Ortholog: 14q11.2-q12 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:leukotriene B4 receptor activity; nucleotide binding; leukotriene receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; muscle contraction; immune response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); cell motility; inflammatory response |
| UniProt Code: | Q15722 |
| NCBI GenInfo Identifier: | 221218998 |
| NCBI Gene ID: | 1241 |
| NCBI Accession: | NP_001137391.1 |
| UniProt Secondary Accession: | Q15722,Q13305, Q53XV5, Q92641, Q9BSU5, |
| UniProt Related Accession: | Q15722 |
| Molecular Weight: | 37,557 Da |
| NCBI Full Name: | leukotriene B4 receptor 1 |
| NCBI Synonym Full Names: | leukotriene B4 receptor |
| NCBI Official Symbol: | LTB4R |
| NCBI Official Synonym Symbols: | BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1 |
| NCBI Protein Information: | leukotriene B4 receptor 1; G protein-coupled receptor 16; G-protein coupled receptor 16; LTB4-R 1; LTB4-R1; P2Y purinoceptor 7; chemoattractant receptor-like 1; chemokine receptor-like 1; purinergic receptor P2Y, G-protein coupled, 7 |
| UniProt Protein Name: | Leukotriene B4 receptor 1 |
| UniProt Synonym Protein Names: | Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7 |
| Protein Family: | Multidrug-efflux transporter 2 regulator |
| UniProt Gene Name: | LTB4R |
| UniProt Entry Name: | LT4R1_HUMAN |
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