Anti-LSP1 Antibody (CAB3355)
- SKU:
- CAB3355
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- WP34
- Synonyms:
- pp52
- Research Area:
- Cell Biology
Description
| Product Name: | LSP1 Rabbit mAb |
| Product Code: | CAB3355 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | WP34, pp52 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human LSP1 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Raji, Mouse spleen, Mouse thymus, Rat lung |
| Immunogen: | A synthesized peptide derived from human LSP1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4046 |
| Uniprot: | P33241 |
| Cellular Location: | Cell membrane, Cytoplasmic side, Peripheral membrane protein |
| Calculated MW: | 52kDa |
| Observed MW: | 47kDa |
| UniProt Protein Function: | LSP1: May play a role in mediating neutrophil activation and chemotaxis. Binds actin. Activated T-lymphocytes. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Actin-binding Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: membrane; plasma membrane; actin cytoskeleton Molecular Function:signal transducer activity; actin binding Biological Process: cellular defense response; cell motility; signal transduction; chemotaxis |
| NCBI Summary: | This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P33241 |
| NCBI GenInfo Identifier: | 462553 |
| NCBI Gene ID: | 4046 |
| NCBI Accession: | P33241.1 |
| UniProt Secondary Accession: | P33241,Q16096, Q53H48, Q6FHM3, Q9BUY8, B3KPP1, B3KRR6 E9PBV6, E9PFP3, |
| UniProt Related Accession: | P33241 |
| Molecular Weight: | 339 |
| NCBI Full Name: | Lymphocyte-specific protein 1 |
| NCBI Synonym Full Names: | lymphocyte-specific protein 1 |
| NCBI Official Symbol: | LSP1 |
| NCBI Official Synonym Symbols: | WP34; pp52 |
| NCBI Protein Information: | lymphocyte-specific protein 1; 52 kDa phosphoprotein; 47 kDa actin binding protein; 47 kDa actin-binding protein; leukocyte-specific protein 1; lymphocyte-specific antigen WP34; leufactin (leukocyte F-actin binding protein); F-actin binding and cytoskeleton associated protein |
| UniProt Protein Name: | Lymphocyte-specific protein 1 |
| UniProt Synonym Protein Names: | 47 kDa actin-binding protein; 52 kDa phosphoprotein; pp52; Lymphocyte-specific antigen WP34 |
| Protein Family: | Lymphocyte-specific protein |
| UniProt Gene Name: | LSP1 |
| UniProt Entry Name: | LSP1_HUMAN |
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