Epigenetics & Nuclear Signaling Antibodies 4
Anti-LSM11 Antibody (CAB7516)
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- SKU:
- CAB7516
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-LSM11 Antibody |
| Antibody SKU: | CAB7516 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_775762.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | Jurkat, HepG2, MCF7, HL-60, Rat brain, Rat pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_775762.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RRGP GRSR KAPR NVLT RMPL HEGS PLGE LHRC IREG VKVN VHIR TFKG LRGV CTGF LVAF DKFW NMAL TDVD ETYR KPVL GKAY ERDS SLTL TRLF DRLK LQDS SKKE ADSK SAVE DSTL SRYS QTST WKLA SVWG RADT GRGS HKRS RSVP SSLQ ASAR EESR SELS GRTT RTDG SSVG GTFS RATT LSRG QSRK KKRK PKVD YQQV FTRH INQI FIRG ENVL LVHL AQ |
| Gene ID: | 134353 |
| Uniprot: | P83369 |
| Cellular Location: | Nucleus |
| Calculated MW: | 39kDa |
| Observed MW: | 45kDa |
| Synonyms: | LSM11 |
| Background: |
| UniProt Protein Function: | LSM11: Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA. Belongs to the snRNP Sm proteins family. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 5q33.3 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding Biological Process: transcription from RNA polymerase II promoter; histone mRNA metabolic process; histone mRNA 3'-end processing; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription |
| UniProt Code: | P83369 |
| NCBI GenInfo Identifier: | 47117879 |
| NCBI Gene ID: | 134353 |
| NCBI Accession: | P83369.2 |
| UniProt Secondary Accession: | P83369,Q7Z7P0, Q8N975, A0AVQ1, |
| UniProt Related Accession: | P83369 |
| Molecular Weight: | 360 |
| NCBI Full Name: | U7 snRNA-associated Sm-like protein LSm11 |
| NCBI Synonym Full Names: | LSM11, U7 small nuclear RNA associated |
| NCBI Official Symbol: | LSM11 |
| NCBI Protein Information: | U7 snRNA-associated Sm-like protein LSm11 |
| UniProt Protein Name: | U7 snRNA-associated Sm-like protein LSm11 |
| Protein Family: | U7 snRNA-associated Sm-like protein |
| UniProt Gene Name: | LSM11 |
| UniProt Entry Name: | LSM11_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LSM11 antibody (CAB7516) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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