Epigenetics & Nuclear Signaling Antibodies 3
Anti-LSM10 Antibody (CAB16586)
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- SKU:
- CAB16586
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-LSM10 Antibody |
| Antibody SKU: | CAB16586 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-123 of human LSM10 (NP_116270.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat spleen, Rat lung, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-123 of human LSM10 (NP_116270.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAVS HSVK ERTI SENS LIIL LQGL QGRV TTVD LRDE SVAH GRID NVDA FMNI RLAK VTYT DRWG HQVK LDDL FVTG RNVR YVHI PDDV NITS TIEQ QLQI IHRV RNFG GKGQ GRWE FPPK NCK |
| Gene ID: | 84967 |
| Uniprot: | Q969L4 |
| Cellular Location: | Nucleus |
| Calculated MW: | 14kDa |
| Observed MW: | 14kDa |
| Synonyms: | LSM10, MST074, MSTP074 |
| Background: |
| UniProt Protein Function: | LSM10: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. Belongs to the snRNP Sm proteins family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1p34.3 Cellular Component: nucleoplasm; Cajal body; nucleus Molecular Function:protein binding Biological Process: transcription from RNA polymerase II promoter; RNA splicing; histone mRNA metabolic process; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription |
| UniProt Code: | Q969L4 |
| NCBI GenInfo Identifier: | 751868069 |
| NCBI Gene ID: | 84967 |
| NCBI Accession: | NP_116270.1 |
| UniProt Related Accession: | Q969L4 |
| Molecular Weight: | 14,080 Da |
| NCBI Full Name: | Homo sapiens LSM10, U7 small nuclear RNA associated (LSM10), mRNA |
| NCBI Synonym Full Names: | LSM10, U7 small nuclear RNA associated |
| NCBI Official Symbol: | LSM10 |
| NCBI Official Synonym Symbols: | MST074; MSTP074 |
| NCBI Protein Information: | U7 snRNA-associated Sm-like protein LSm10; U7 snRNP-specific Sm-like protein LSM10 |
| UniProt Protein Name: | U7 snRNA-associated Sm-like protein LSm10 |
| Protein Family: | U7 snRNA-associated Sm-like protein |
| UniProt Gene Name: | LSM10 |
| UniProt Entry Name: | LSM10_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LSM10 antibody (CAB16586) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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