Neuroscience
Anti-LRRC4C Antibody (CAB15491)
- SKU:
- CAB15491
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Description
| Antibody Name: | Anti-LRRC4C Antibody |
| Antibody SKU: | CAB15491 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 450-520 of human LRRC4C (NP_065980.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat eye |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 450-520 of human LRRC4C (NP_065980.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PFSY FSTV TVET MEPS QDEA RTTD NNVG PTPV VDWE TTNV TTSL TPQS TRST EKTF TIPV TDIN SGIP GID |
| Gene ID: | 57689 |
| Uniprot: | Q9HCJ2 |
| Cellular Location: | Cell junction, Single-pass type I membrane protein, postsynaptic cell membrane, synapse |
| Calculated MW: | 71kDa |
| Observed MW: | 72kDa |
| Synonyms: | LRRC4C, NGL-1, NGL1 |
| Background: |
| UniProt Protein Function: | LRRC4C: May promote neurite outgrowth of developing thalamic neurons. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell development/differentiation Chromosomal Location of Human Ortholog: 11p12 Cellular Component: postsynaptic membrane; extracellular space; membrane; integral to membrane; cell junction Molecular Function:protein binding Biological Process: regulation of axonogenesis |
| NCBI Summary: | NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9HCJ2 |
| NCBI GenInfo Identifier: | 57012973 |
| NCBI Gene ID: | 57689 |
| NCBI Accession: | Q9HCJ2.1 |
| UniProt Related Accession: | Q9HCJ2 |
| Molecular Weight: | 71kDa |
| NCBI Full Name: | Leucine-rich repeat-containing protein 4C |
| NCBI Synonym Full Names: | leucine rich repeat containing 4C |
| NCBI Official Symbol: | LRRC4C |
| NCBI Official Synonym Symbols: | NGL1; NGL-1 |
| NCBI Protein Information: | leucine-rich repeat-containing protein 4C |
| UniProt Protein Name: | Leucine-rich repeat-containing protein 4C |
| UniProt Synonym Protein Names: | Netrin-G1 ligand; NGL-1 |
| Protein Family: | Leucine-rich repeat-containing protein |
| UniProt Gene Name: | LRRC4C |
| UniProt Entry Name: | LRC4C_HUMAN |
 | Western blot analysis of extracts of rat eye, using LRRC4C antibody (CAB15491) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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