Neuroscience

Anti-LRRC4C Antibody (CAB15491)

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SKU:
CAB15491
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience

Description

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Antibody Name:Anti-LRRC4C Antibody
Antibody SKU:CAB15491
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 450-520 of human LRRC4C (NP_065980.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Rat
Positive Samples:Rat eye
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 450-520 of human LRRC4C (NP_065980.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PFSY FSTV TVET MEPS QDEA RTTD NNVG PTPV VDWE TTNV TTSL TPQS TRST EKTF TIPV TDIN SGIP GID
Gene ID:57689
Uniprot:Q9HCJ2
Cellular Location:Cell junction, Single-pass type I membrane protein, postsynaptic cell membrane, synapse
Calculated MW:71kDa
Observed MW:72kDa
Synonyms:LRRC4C, NGL-1, NGL1
Background:
UniProt Protein Function:LRRC4C: May promote neurite outgrowth of developing thalamic neurons.
UniProt Protein Details:

Protein type:Membrane protein, integral; Cell development/differentiation

Chromosomal Location of Human Ortholog: 11p12

Cellular Component: postsynaptic membrane; extracellular space; membrane; integral to membrane; cell junction

Molecular Function:protein binding

Biological Process: regulation of axonogenesis

NCBI Summary:NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]).[supplied by OMIM, Mar 2008]
UniProt Code:Q9HCJ2
NCBI GenInfo Identifier:57012973
NCBI Gene ID:57689
NCBI Accession:Q9HCJ2.1
UniProt Related Accession:Q9HCJ2
Molecular Weight:71kDa
NCBI Full Name:Leucine-rich repeat-containing protein 4C
NCBI Synonym Full Names:leucine rich repeat containing 4C
NCBI Official Symbol:LRRC4C  
NCBI Official Synonym Symbols:NGL1; NGL-1  
NCBI Protein Information:leucine-rich repeat-containing protein 4C
UniProt Protein Name:Leucine-rich repeat-containing protein 4C
UniProt Synonym Protein Names:Netrin-G1 ligand; NGL-1
Protein Family:Leucine-rich repeat-containing protein
UniProt Gene Name:LRRC4C  
UniProt Entry Name:LRC4C_HUMAN
Anti-LRRC4C Antibody (CAB15491)Western blot analysis of extracts of rat eye, using LRRC4C antibody (CAB15491) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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