Cell Biology Antibodies 13
Anti-LPCAT3 Antibody (CAB17604)
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- SKU:
- CAB17604
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-LPCAT3 Antibody |
| Antibody SKU: | CAB17604 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-370 of human LPCAT3 (NP_005759.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse testis, Mouse pancreas, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-370 of human LPCAT3 (NP_005759.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | FDGG KDQN SLSS EQQK YAIR GVPS LLEV AGFS YFYG AFLV GPQF SMNH YMKL VQGE LIDI PGKI PNSI IPAL KRLS LGLF YLVG YTLL SPHI TEDY LLTE DYDN HPFW FRCM YMLI WGKF VLYK YVTC WLVT EGVC ILTG LGFN GFEE KGKA KWDA CANM KVWL FETN PRFT GTIA SFNI NTNA WVAR YIFK RLKF LGNK ELSQ GLSL LFL |
| Gene ID: | 10162 |
| Uniprot: | Q6P1A2 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 56kDa |
 | Western blot - LPCAT3 Polyclonal Antibody (CAB17604) |
| Synonyms: | C3F, LPCAT, LPLAT 5, LPSAT, MBOAT5, OACT5, nessy, LPCAT3 |
| Background: |
| UniProt Protein Function: | MBOAT5: Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3- phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero- 3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. Belongs to the membrane-bound acyltransferase family. |
| UniProt Protein Details: | Protein type:EC 2.3.1.23; EC 2.3.1.n6; Membrane protein, integral; Membrane protein, multi-pass; Transferase Chromosomal Location of Human Ortholog: 12p13.31 Cellular Component: endoplasmic reticulum membrane; integral component of membrane; membrane Molecular Function:1-acylglycerol-3-phosphate O-acyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity Biological Process: phospholipid biosynthetic process |
| UniProt Code: | Q6P1A2 |
| NCBI GenInfo Identifier: | 42542394 |
| NCBI Gene ID: | 10162 |
| NCBI Accession: | NP_005759.4 |
| UniProt Secondary Accession: | Q6P1A2,Q7KZS1, Q92980, Q9BW40, B2RDH0, B7Z3N3, |
| UniProt Related Accession: | Q6P1A2 |
| Molecular Weight: | |
| NCBI Full Name: | lysophospholipid acyltransferase 5 |
| NCBI Synonym Full Names: | lysophosphatidylcholine acyltransferase 3 |
| NCBI Official Symbol: | LPCAT3 |
| NCBI Official Synonym Symbols: | C3F; LPCAT; LPSAT; OACT5; nessy; MBOAT5; LPLAT 5 |
| NCBI Protein Information: | lysophospholipid acyltransferase 5 |
| UniProt Protein Name: | Lysophospholipid acyltransferase 5 |
| UniProt Synonym Protein Names: | 1-acylglycerophosphocholine O-acyltransferase (EC:2.3.1.23); 1-acylglycerophosphoserine O-acyltransferase (EC:2.3.1.n6); Lysophosphatidylcholine acyltransferase; LPCAT; Lyso-PC acyltransferase; Lysophosphatidylcholine acyltransferase 3; Lyso-PC acyltransferase 3; Lysophosphatidylserine acyltransferase; LPSAT; Lyso-PS acyltransferase; Membrane-bound O-acyltransferase domain-containing protein 5; O-acyltransferase domain-containing protein 5 |
| Protein Family: | Lysophospholipid acyltransferase |
| UniProt Gene Name: | LPCAT3 |
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