Cell Biology Antibodies 5
Anti-LPAR3 Antibody (CAB15144)
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- SKU:
- CAB15144
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-LPAR3 Antibody |
| Antibody SKU: | CAB15144 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human LPAR3 (NP_036284.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human LPAR3 (NP_036284.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LLVW AIAI FMGA VPTL GWNC LCNI SACS SLAP IYSR SYLV FWTV SNLM AFLI MVVV YLRI YVYV KRKT NVLS PHTS GSIS RRRT PMKL MKTV MTVL GAFV V |
| Gene ID: | 23566 |
| Uniprot: | Q9UBY5 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 40kDa |
| Observed MW: | Refer to figures |
| Synonyms: | LPAR3, EDG7, Edg-7, GPCR, HOFNH30, LP-A3, LPA3, RP4-678I3 |
| Background: | This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. |
| UniProt Protein Function: | EDG7: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Motility/polarity/chemotaxis; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p22.3 Cellular Component: integral to plasma membrane; axon; plasma membrane Molecular Function:G-protein coupled receptor activity; G-protein alpha-subunit binding; phospholipid binding; lipid binding Biological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); activation of MAPK activity; bleb formation; positive regulation of calcium ion transport; positive regulation of collateral sprouting |
| NCBI Summary: | This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UBY5 |
| NCBI GenInfo Identifier: | 26393418 |
| NCBI Gene ID: | 23566 |
| NCBI Accession: | Q9UBY5.1 |
| UniProt Secondary Accession: | Q9UBY5,A0AVA3, |
| UniProt Related Accession: | Q9UBY5 |
| Molecular Weight: | 40,128 Da |
| NCBI Full Name: | Lysophosphatidic acid receptor 3 |
| NCBI Synonym Full Names: | lysophosphatidic acid receptor 3 |
| NCBI Official Symbol: | LPAR3 |
| NCBI Official Synonym Symbols: | EDG7; GPCR; LPA3; Edg-7; LP-A3; HOFNH30; RP4-678I3 |
| NCBI Protein Information: | lysophosphatidic acid receptor 3; LPA receptor 3; LPA receptor EDG7; LPA-3; calcium-mobilizing lysophosphatidic acid receptor LP-A3; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; lysophosphatidic acid receptor Edg-7 |
| UniProt Protein Name: | Lysophosphatidic acid receptor 3 |
| UniProt Synonym Protein Names: | Lysophosphatidic acid receptor Edg-7 |
| Protein Family: | Lysophosphatidic acid receptor |
| UniProt Gene Name: | LPAR3 |
| UniProt Entry Name: | LPAR3_HUMAN |
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