Anti-LORICRIN Antibody (CAB21039)
- SKU:
- CAB21039
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Anti-LORICRIN Antibody (CAB21039) |
| Antibody SKU: | CAB21039 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting, Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LORICRIN (NP_000418.2). |
| Application: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse skin, Rat skin |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LORICRIN (NP_000418.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSYQ KKQP TPQP PVDC VKTS GGGG GGGG SGGG GCGF FGGG GSGG GSSG SGCG YSGG GGYS GGGC GGGS SGGG GGGG IGGC GGGS GGSV KYSG GGGS SGGG |
| Cellular Location: | |
| Calculated MW: | 25kDa |
| Observed MW: | 26KDa |
| Synonyms: | LOR |
| Background: | This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. |
 | Immunofluorescence analysis of mouse skin using LORICRIN Rabbit pAb at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of A431 cells using LORICRIN Rabbit pAb at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of rat skin using LORICRIN Rabbit pAb at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining. |
 | Western blot analysis of extracts of various cell lines, using LORICRIN antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s. |
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