Cell Biology Antibodies 10
Anti-LMOD1 Antibody (CAB7087)
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- SKU:
- CAB7087
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-LMOD1 Antibody |
| Antibody SKU: | CAB7087 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-187 of human LMOD1 (NP_036266.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-187 of human LMOD1 (NP_036266.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEEL EKEL DVVD PDGS VPVG LRQR NQTE KQST GVYN REAM LNFC EKET KKLM QREM SMDE SKQV ETKT DAKN GEER GRDA SKKA LGPR RDSD LGKE PKRG GLKK SFSR DRDE AGGK SGEK PKEE KIIR GIDK GRVR AAVD KKEA GKDG RGEE RAVA TKK |
| Gene ID: | 25802 |
| Uniprot: | P29536 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 63kDa/67kDa |
| Observed MW: | Refer to figures |
| Synonyms: | LMOD1, 1D, 64kD, D1, SM-LMOD, SMLMOD |
| Background: | The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. |
| UniProt Protein Function: | LMOD1: The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q32 Cellular Component: membrane; cytosol; striated muscle thin filament Molecular Function:actin binding; tropomyosin binding Biological Process: myofibril assembly; muscle contraction; actin filament organization; pointed-end actin filament capping |
| NCBI Summary: | The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P29536 |
| NCBI GenInfo Identifier: | 325511399 |
| NCBI Gene ID: | 25802 |
| NCBI Accession: | P29536.3 |
| UniProt Related Accession: | P29536 |
| Molecular Weight: | 63kDa; 67kDa |
| NCBI Full Name: | Leiomodin-1 |
| NCBI Synonym Full Names: | leiomodin 1 |
| NCBI Official Symbol: | LMOD1 |
| NCBI Official Synonym Symbols: | 1D; D1; 64kD; SMLMOD; SM-LMOD |
| NCBI Protein Information: | leiomodin-1 |
| UniProt Protein Name: | Leiomodin-1 |
| UniProt Synonym Protein Names: | 64 kDa autoantigen 1D; 64 kDa autoantigen 1D3; 64 kDa autoantigen D1; Leiomodin, muscle form; Smooth muscle leiomodin; SM-Lmod; Thyroid-associated ophthalmopathy autoantigen |
| Protein Family: | Leiomodin |
| UniProt Gene Name: | LMOD1 |
| UniProt Entry Name: | LMOD1_HUMAN |
 | Immunohistochemistry of paraffin-embedded human colon using LMOD1 antibody (CAB7087) at dilution of 1:200 (40x lens). |
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