Cell Biology Antibodies 15
Anti-LLGL2 Antibody (CAB8099)
- SKU:
- CAB8099
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Description
Antibody Name: | Anti-LLGL2 Antibody |
Antibody SKU: | CAB8099 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 900-1000 of mouse LLGL2 (NP_663413.2). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
Reactivity: | Human, Mouse |
Positive Samples: | 293T, HepG2, Mouse lung, Mouse testis |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 900-1000 of mouse LLGL2 (NP_663413.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | IASC VFTK YGQG FYLI SPSE FERF SLST KWLV EPRC LVDS TKAK KHNR PSNG NGTG LKMT SSGH VRNS KSQS DGDE KKPG PVME HALL NDAW VLKE IQST L |
Gene ID: | 217325 |
Uniprot: | |
Cellular Location: | Cytoplasm |
Calculated MW: | 114kDa |
Observed MW: | 114kDa |
Synonyms: | LLGL2, HGL, Hugl-2, LGL2 |
Background: | The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. |