| UniProt Protein Function: | Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15334 |
| NCBI GenInfo Identifier: | 259016343 |
| NCBI Gene ID: | 3996 |
| NCBI Accession: | Q15334.3 |
| UniProt Secondary Accession: | Q15334,O00188, Q58F11, Q86UK6, A7MBM7 |
| UniProt Related Accession: | Q15334 |
| Molecular Weight: | 115,418 Da |
| NCBI Full Name: | Lethal(2) giant larvae protein homolog 1 |
| NCBI Synonym Full Names: | LLGL scribble cell polarity complex component 1 |
| NCBI Official Symbol: | LLGL1 |
| NCBI Official Synonym Symbols: | DLG4; HUGL; LLGL; Lgl1; Mgl1; HUGL1; HUGL-1 |
| NCBI Protein Information: | lethal(2) giant larvae protein homolog 1 |
| UniProt Protein Name: | Lethal(2) giant larvae protein homolog 1 |
| UniProt Synonym Protein Names: | DLG4; Hugl-1; Human homolog to the D-lgl gene protein |
| Protein Family: | Lethal(2) giant larvae protein |
| UniProt Gene Name: | LLGL1 |
| UniProt Entry Name: | |
