Immunology Antibodies 2
Anti-LILRA2 Antibody (CAB4477)
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- SKU:
- CAB4477
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- LILRA2
- Synonyms:
- CD85H
- Synonyms:
- ILT1
- Synonyms:
- LIR-7
- Synonyms:
- LIR7
- Research Area:
- Immunology
Description
| Product Name: | LILRA2 Rabbit pAb |
| Product Code: | CAB4477 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | LILRA2, CD85H, ILT1, LIR-7, LIR7 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-240 of human LILRA2 (NP_006857.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | B cells, LO2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-240 of human LILRA2 (NP_006857.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GHLP KPTL WAEP GSVI IQGS PVTL RCQG SLQA EEYH LYRE NKSA SWVR RIQE PGKN GQFP IPSI TWEH AGRY HCQY YSHN HSSE YSDP LELV VTGA YSKP TLSA LPSP VVTS GGNV TLQC VSQV AFDG FILC KEGE DEHP QRLN SHSH ARGW SWAI FSVG PVSP SRRW SYRC YAYD SNSP YVWS LPSD LLEL LVPG VSKK PSLS VQPG PMVA PGES L |
| Gene ID: | 11027 |
| Uniprot: | Q8N149 |
| Cellular Location: | Membrane, Secreted, Single-pass type I membrane protein |
| Calculated MW: | 46kDa/48kDa/51kDa/52kDa |
| Observed MW: | 53kDa |
| UniProt Protein Function: | LILRA2: Does not bind class I MHC antigens. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.4 Cellular Component: extracellular region; integral to membrane Molecular Function:receptor activity; antigen binding Biological Process: immune system process; defense response; signal transduction |
| NCBI Summary: | This gene encodes a member of a family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and there is a pseudogene for this gene on chromosome 3. [provided by RefSeq, Mar 2014] |
| UniProt Code: | Q8N149 |
| NCBI GenInfo Identifier: | 37537906 |
| NCBI Gene ID: | 11027 |
| NCBI Accession: | Q8N149.2 |
| UniProt Secondary Accession: | Q8N149,O75020, |
| UniProt Related Accession: | Q8N149 |
| Molecular Weight: | 483 |
| NCBI Full Name: | Leukocyte immunoglobulin-like receptor subfamily A member 2 |
| NCBI Synonym Full Names: | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| NCBI Official Symbol: | LILRA2 |
| NCBI Official Synonym Symbols: | ILT1; LIR7; CD85H; LIR-7 |
| NCBI Protein Information: | leukocyte immunoglobulin-like receptor subfamily A member 2; immunoglobulin-like transcript 1; CD85 antigen-like family member H; leukocyte immunoglobulin-like receptor 7; leukocyte immunoglobulin-like receptor subfamily A member 2 soluble |
| UniProt Protein Name: | Leukocyte immunoglobulin-like receptor subfamily A member 2 |
| UniProt Synonym Protein Names: | CD85 antigen-like family member H; Immunoglobulin-like transcript 1; ILT-1; Leukocyte immunoglobulin-like receptor 7; LIR-7; CD_antigen: CD85h |
| Protein Family: | Leukocyte immunoglobulin-like receptor subfamily |
| UniProt Gene Name: | LILRA2 |
| UniProt Entry Name: | LIRA2_HUMAN |
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