Epigenetics & Nuclear Signaling Antibodies 1
Anti-LHX2 Antibody (CAB10803)
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- SKU:
- CAB10803
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-LHX2 Antibody |
| Antibody SKU: | CAB10803 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 337-406 of human LHX2 (NP_004780.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | NCI-H460 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 337-406 of human LHX2 (NP_004780.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TDAA LQTG TPSG PASE LSNA SLSP SSTP TTLT DLTS PTLP TVTS VLTS VPGN LEGH EPHS PSQT TLTN LF |
| Gene ID: | 9355 |
| Uniprot: | P50458 |
| Cellular Location: | Nucleus |
| Calculated MW: | 44kDa |
| Observed MW: | 44kDa |
| Synonyms: | LHX2, LH2, hLhx2 |
| Background: | This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. |
| UniProt Protein Function: | LHX2: Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 9q33.3 Biological Process: positive regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P50458 |
| NCBI GenInfo Identifier: | 8247936 |
| NCBI Gene ID: | 9355 |
| NCBI Accession: | P50458.2 |
| UniProt Secondary Accession: | P50458,O95860, Q52M57, Q8N1Z3, |
| UniProt Related Accession: | P50458 |
| Molecular Weight: | 44kDa |
| NCBI Full Name: | LIM/homeobox protein Lhx2 |
| NCBI Synonym Full Names: | LIM homeobox 2 |
| NCBI Official Symbol: | LHX2 |
| NCBI Official Synonym Symbols: | LH2; hLhx2 |
| NCBI Protein Information: | LIM/homeobox protein Lhx2 |
| UniProt Protein Name: | LIM/homeobox protein Lhx2 |
| Protein Family: | LIM/homeobox protein |
| UniProt Gene Name: | LHX2 |
 | Western blot analysis of extracts of H460 cells, using LHX2 antibody (CAB10803) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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