Cell Biology Antibodies 8
Anti-LETMD1 Antibody (CAB2147)
(No reviews yet)
Write a Review
- SKU:
- CAB2147
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-LETMD1 Antibody |
| Antibody SKU: | CAB2147 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-360 of human LETMD1 (NP_056231.3). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-360 of human LETMD1 (NP_056231.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | FPRQ LLIR HFWT PKQQ TDFL DIYH AFRK QSHP EIIS YLEK VIPL ISDA GLRW RLTD LCTK IQRG THPA IHDI LALR ECFS NHPL GMNQ LQAL HVKA LSRA MLLT SYLP PPLL RHRL KTHT TVIH QLDK ALAK LGIG QLTA QEVK SACY LRGL NSTH IGED RCRT WLGE WLQI SCSL KEAE LSLL LHNV VLLS TNYL GTRR |
| Gene ID: | 25875 |
| Uniprot: | Q6P1Q0 |
| Cellular Location: | Mitochondrion outer membrane, Single-pass membrane protein |
| Calculated MW: | 11kDa/17kDa/23kDa/35kDa/41kDa/43kDa |
| Observed MW: | 41kDa |
| Synonyms: | LETMD1, 1110019O13Rik, HCCR, HCCR-1, HCCR-2, HCCR1, HCCR2, HCRR-2 |
| Background: | This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. |
| UniProt Protein Function: | LETMD1: Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Oncoprotein; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q13.12 Cellular Component: mitochondrial outer membrane; integral to membrane Molecular Function:protein binding |
| NCBI Summary: | This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q6P1Q0 |
| NCBI GenInfo Identifier: | 74737159 |
| NCBI Gene ID: | 25875 |
| NCBI Accession: | Q6P1Q0.1 |
| UniProt Related Accession: | Q6P1Q0 |
| Molecular Weight: | |
| NCBI Full Name: | LETM1 domain-containing protein 1 |
| NCBI Synonym Full Names: | LETM1 domain containing 1 |
| NCBI Official Symbol: | LETMD1 |
| NCBI Official Synonym Symbols: | HCCR; HCCR1; HCCR2; HCCR-1; HCCR-2; HCRR-2; SLC55A3; 1110019O13Rik |
| NCBI Protein Information: | LETM1 domain-containing protein 1 |
| UniProt Protein Name: | LETM1 domain-containing protein 1 |
| UniProt Synonym Protein Names: | Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2 |
| Protein Family: | LETM1 domain-containing protein |
| UniProt Gene Name: | LETMD1 |
| UniProt Entry Name: | LTMD1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LETMD1 antibody (CAB2147) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded Human colon using LETMD1 Rabbit pAb (CAB2147) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Mouse kidney using LETMD1 Rabbit pAb (CAB2147) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Rat testis using LETMD1 Rabbit pAb (CAB2147) at dilution of 1:100 (40x lens). |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक