Signal Transduction Antibodies 2

Anti-LDHC Antibody (CAB15003)

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SKU:
CAB15003
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-LDHC Antibody
Antibody SKU:CAB15003
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human LDHC (NP_002292.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, A549, Mouse lung, Rat brain
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human LDHC (NP_002292.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ISGL PVTR VIGS GCNL DSAR FRYL IGEK LGVH PTSC HGWI IGEH GDSS VPLW SGVN VAGV ALKT LDPK LGTD SDKE HWKN IHKQ VIQS AYEI IKLK GYTS W
Gene ID:3948
Uniprot:P07864
Cellular Location:Cytoplasm
Calculated MW:36kDa
Observed MW:36kDa
Synonyms:LDHC, CT32, LDH3, LDHX
Background: Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region.
UniProt Protein Function:LDH-C: Possible role in sperm motility. Belongs to the LDH/MDH superfamily. LDH family.
UniProt Protein Details:

Protein type:Amino Acid Metabolism - cysteine and methionine; Cancer Testis Antigen (CTA); Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - pyruvate; EC 1.1.1.27; Oxidoreductase

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: cytosol; nucleus

Molecular Function:L-lactate dehydrogenase activity

Biological Process: pyruvate metabolic process

NCBI Summary:Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region. [provided by RefSeq, Jul 2008]
UniProt Code:P07864
NCBI GenInfo Identifier:4504973
NCBI Gene ID:3948
NCBI Accession:NP_002292.1
UniProt Secondary Accession:P07864,Q6GSG8, Q7Z7J4, D3DQY4,
UniProt Related Accession:P07864
Molecular Weight:
NCBI Full Name:L-lactate dehydrogenase C chain
NCBI Synonym Full Names:lactate dehydrogenase C
NCBI Official Symbol:LDHC  
NCBI Official Synonym Symbols:CT32; LDH3; LDHX  
NCBI Protein Information:L-lactate dehydrogenase C chain
UniProt Protein Name:L-lactate dehydrogenase C chain
UniProt Synonym Protein Names:Cancer/testis antigen 32; CT32; LDH testis subunit; LDH-X
Protein Family:L-lactate dehydrogenase
UniProt Gene Name:LDHC  
UniProt Entry Name:LDHC_HUMAN
Anti-LDHC Antibody (CAB15003)Western blot analysis of extracts of various cell lines, using LDHC antibody (CAB15003) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-LDHC Antibody (CAB15003)Immunofluorescence analysis of rat testis using LDHC Polyclonal Antibody (CAB15003) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Anti-LDHC Antibody (CAB15003)Immunofluorescence analysis of mouse testis using LDHC Polyclonal Antibody (CAB15003) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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