Immunology Antibodies 2

Anti-LAMP3 Antibody (CAB2895)

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SKU:
CAB2895
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology

Description

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Antibody Name:Anti-LAMP3 Antibody
Antibody SKU:CAB2895
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human LAMP3
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:Raji, HT-29, A-549, HeLa
Immunogen:A synthetic peptide of human LAMP3
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:27074
Uniprot:Q9UQV4
Cellular Location:Cytoplasmic vesicle membrane, Lysosome membrane, Single-pass type I membrane protein
Calculated MW:44kDa
Observed MW:75kDa
Synonyms:LAMP3, CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403
Background:Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).
UniProt Protein Function:LAMP3: Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells. Belongs to the LAMP family.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q26.3-q27

Cellular Component: lysosomal membrane; integral to membrane

Biological Process: cell proliferation; immune system process

NCBI Summary:Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]
UniProt Code:Q9UQV4
NCBI GenInfo Identifier:38455385
NCBI Gene ID:27074
NCBI Accession:NP_055213.2
UniProt Secondary Accession:Q9UQV4,O94781, Q8NEC8, D3DNS4,
UniProt Related Accession:Q9UQV4
Molecular Weight:44,346 Da
NCBI Full Name:lysosome-associated membrane glycoprotein 3
NCBI Synonym Full Names:lysosomal-associated membrane protein 3
NCBI Official Symbol:LAMP3  
NCBI Official Synonym Symbols:LAMP; CD208; DCLAMP; LAMP-3; TSC403; DC LAMP; DC-LAMP  
NCBI Protein Information:lysosome-associated membrane glycoprotein 3; DC-lysosome-associated membrane glycoprotein
UniProt Protein Name:Lysosome-associated membrane glycoprotein 3
UniProt Synonym Protein Names:DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403
Protein Family:Lysosome-associated membrane glycoprotein
UniProt Gene Name:LAMP3  
UniProt Entry Name:LAMP3_HUMAN
Anti-LAMP3 Antibody (CAB2895)Western blot analysis of extracts of various cell lines, using LAMP3 antibody (CAB2895) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min.
Anti-LAMP3 Antibody (CAB2895)Immunohistochemistry of paraffin-embedded rat brain using LAMP3 antibody (CAB2895) at dilution of 1:200 (40x lens).
Anti-LAMP3 Antibody (CAB2895)Immunohistochemistry of paraffin-embedded mouse heart using LAMP3 antibody (CAB2895) at dilution of 1:200 (40x lens).
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