Immunology Antibodies 2
Anti-LAMP1 Antibody (CAB16895)
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- SKU:
- CAB16895
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-LAMP1 Antibody |
| Antibody SKU: | CAB16895 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human LAMP1. |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse lung, Mouse kidney, Rat liver |
| Immunogen: | Recombinant protein of human LAMP1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3916 |
| Uniprot: | P11279 |
| Cellular Location: | Cell membrane, Endosome membrane, Late endosome, Lysosome membrane, Single-pass type I membrane protein |
| Calculated MW: | 38kDa/44kDa |
| Observed MW: | 120KDa |
| Synonyms: | LAMP1, CD107a, LAMPA, LGP120 |
| Background: | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. |
| UniProt Protein Function: | LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 13q34 Cellular Component: integral to plasma membrane; lysosome; dendrite; multivesicular body; cell soma; membrane; late endosome; cytoplasm; plasma membrane; melanosome; endosome membrane; sarcolemma; external side of plasma membrane Molecular Function:protein domain specific binding; protein binding; enzyme binding Biological Process: positive regulation of natural killer cell degranulation; induction of apoptosis by granzyme; protein stabilization; viral reproduction; autophagic cell death; autophagy; positive regulation of natural killer cell mediated cytotoxicity |
| NCBI Summary: | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P11279 |
| NCBI GenInfo Identifier: | 206729915 |
| NCBI Gene ID: | 3916 |
| NCBI Accession: | P11279.3 |
| UniProt Secondary Accession: | P11279,Q8WU33, Q96I40, Q9BRD2, Q9NP13, B4DWL3, |
| UniProt Related Accession: | P11279 |
| Molecular Weight: | 417 |
| NCBI Full Name: | Lysosome-associated membrane glycoprotein 1 |
| NCBI Synonym Full Names: | lysosomal-associated membrane protein 1 |
| NCBI Official Symbol: | LAMP1 |
| NCBI Official Synonym Symbols: | LAMPA; CD107a; LGP120 |
| NCBI Protein Information: | lysosome-associated membrane glycoprotein 1; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1 |
| UniProt Protein Name: | Lysosome-associated membrane glycoprotein 1 |
| UniProt Synonym Protein Names: | CD107 antigen-like family member A; CD_antigen: CD107a |
| Protein Family: | Lysosome-associated membrane glycoprotein |
| UniProt Gene Name: | LAMP1 |
| UniProt Entry Name: | LAMP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LAMP1 antibody (CAB16895) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Western blot analysis of extracts of Rat liver, using LAMP1 antibody (CAB16895) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of NIH-3T3 cells using LAMP1 Rabbit pAb (CAB16895) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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