Description
Product Name: | LAGE3 Rabbit pAb |
Product Code: | CAB20546 |
Size: | 50uL, 100uL |
Synonyms: | CVG5, ESO3, Pcc1, ITBA2, GAMOS2, DXS9879E, DXS9951E |
Applications: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-143 of human LAGE3 (NP_006005.2). |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | HepG2, NCI-H460, BxPC-3 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-143 of human LAGE3 (NP_006005.2). |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 8270 |
Uniprot: | Q14657 |
Calculated MW: | 14kDa |
Observed MW: | 17KDa |
Background: | This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. |