Cell Biology Antibodies 7
Anti-KSR2 Antibody (CAB17866)
(No reviews yet)
Write a Review
- SKU:
- CAB17866
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-KSR2 Antibody |
| Antibody SKU: | CAB17866 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 780-890 of human KSR2 (NP_775869.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 780-890 of human KSR2 (NP_775869.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ISGV LQAG RRED KLRI QNGW LCHL APEI IRQL SPDT EEDK LPFS KHSD VFAL GTIW YELH AREW PFKT QPAE AIIW QMGT GMKP NLSQ IGMG KEIS DILL FCWA FEQE ERP |
| Gene ID: | 283455 |
| Uniprot: | Q6VAB6 |
| Cellular Location: | |
| Calculated MW: | 108kDa |
| Observed MW: | Refer to figures |
| Synonyms: | KSR2 |
| Background: |
| UniProt Protein Function: | KSR2: Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein kinase, TKL; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); TKL group; RAF family Chromosomal Location of Human Ortholog: 12q24.22-q24.23 Cellular Component: cytoplasm; membrane Molecular Function:ATP binding; metal ion binding; protein serine/threonine kinase activity Biological Process: protein amino acid phosphorylation |
| UniProt Code: | Q6VAB6 |
| NCBI GenInfo Identifier: | 148886599 |
| NCBI Gene ID: | 283455 |
| NCBI Accession: | Q6VAB6.2 |
| UniProt Secondary Accession: | Q6VAB6,Q3B828, Q8N775, A0PJT2, |
| UniProt Related Accession: | Q6VAB6 |
| Molecular Weight: | 49,607 Da |
| NCBI Full Name: | Kinase suppressor of Ras 2 |
| NCBI Synonym Full Names: | kinase suppressor of ras 2 |
| NCBI Official Symbol: | KSR2 |
| NCBI Protein Information: | kinase suppressor of Ras 2 |
| UniProt Protein Name: | Kinase suppressor of Ras 2 |
| Protein Family: | Kinase suppressor of Ras |
| UniProt Gene Name: | KSR2 |
| UniProt Entry Name: | KSR2_HUMAN |
View AllClose
Related Products
Human KSR2 ELISA Kit
Human KSR2 ELISAKSR2 (Kinase Suppressor Of Ras 2) participates in transcriptional activation of multiple genes encoding amino acid transport systems and enzymes involved in their metabolism. It has...
