Cell Biology Antibodies 4

Anti-KRT36 Antibody (CAB13759)

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SKU:
CAB13759
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-KRT36 Antibody
Antibody SKU:CAB13759
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 388-467 of human KRT36 (NP_003762.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Rat
Positive Samples:HeLa, LO2, BxPC-3
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 388-467 of human KRT36 (NP_003762.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GEIA TYRH LLEG EDCK LPPQ PCAT ACKP VIRV PSVP PVPC VPSV PCTP APQV GTQI RTIT EEIR DGKV ISSR EHVQ SRPL
Gene ID:8689
Uniprot:O76013
Cellular Location:
Calculated MW:47kDa/52kDa
Observed MW:52kDa
Synonyms:KRT36, HA6, KRTHA6, hHa6
Background:The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.
UniProt Protein Function:K36: a type I hair keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of hair/microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

NCBI Summary:The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]
UniProt Code:O76013
NCBI GenInfo Identifier:6685565
NCBI Gene ID:8689
NCBI Accession:O76013.1
UniProt Secondary Accession:O76013,Q86XG4,
UniProt Related Accession:O76013
Molecular Weight:47,485 Da
NCBI Full Name:Keratin, type I cuticular Ha6
NCBI Synonym Full Names:keratin 36
NCBI Official Symbol:KRT36  
NCBI Official Synonym Symbols:HA6; hHa6; KRTHA6  
NCBI Protein Information:keratin, type I cuticular Ha6
UniProt Protein Name:Keratin, type I cuticular Ha6
UniProt Synonym Protein Names:Hair keratin, type I Ha6; Keratin-36; K36
Protein Family:Keratin
UniProt Gene Name:KRT36  
UniProt Entry Name:KRT36_HUMAN
Anti-KRT36 Antibody (CAB13759)Western blot analysis of extracts of various cell lines, using KRT36 antibody (CAB13759) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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