Cell Biology Antibodies 14

Anti-KRT23 Antibody (CAB17996)

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SKU:
CAB17996
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-KRT23 Antibody
Antibody SKU:CAB17996
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human KRT23
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant protein of human KRT23
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:25984
Uniprot:Q9C075
Cellular Location:
Calculated MW:33kDa/48kDa
Observed MW:Refer to figures
Synonyms:KRT23, CK23, HAIK1, K23
Background:The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:K23: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: intermediate filament

Molecular Function:structural molecule activity

NCBI Summary:The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Code:Q9C075
NCBI GenInfo Identifier:143811410
NCBI Gene ID:25984
NCBI Accession:Q9C075.2
UniProt Secondary Accession:Q9C075,Q9NUR6, A8K084, B7Z7J2, I3L3Q6,
UniProt Related Accession:Q9C075
Molecular Weight:422
NCBI Full Name:Keratin, type I cytoskeletal 23
NCBI Synonym Full Names:keratin 23 (histone deacetylase inducible)
NCBI Official Symbol:KRT23  
NCBI Official Synonym Symbols:K23; CK23; HAIK1  
NCBI Protein Information:keratin, type I cytoskeletal 23; CK-23; keratin-23; cytokeratin 23; cytokeratin-23; histone deacetylase inducible keratin 23; type I intermediate filament cytokeratin; hyperacetylation-inducible type I keratin
UniProt Protein Name:Keratin, type I cytoskeletal 23
UniProt Synonym Protein Names:Cytokeratin-23; CK-23; Keratin-23; K23
Protein Family:Keratin
UniProt Gene Name:KRT23  
UniProt Entry Name:K1C23_HUMAN
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