Cell Biology Antibodies 8

Anti-KLK15 Antibody (CAB2757)

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SKU:
CAB2757
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-KLK15 Antibody
Antibody SKU:CAB2757
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human KLK15 (NP_059979.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse kidney, Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human KLK15 (NP_059979.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RDGP EQLR TTSR VIPH PRYE ARSH RNDI MLLR LVQP ARLN PQVR PAVL PTRC PHPG EACV VSGW GLVS HNEP GTAG SPRS QVSL PDTL HCAN ISII SDTS C
Gene ID:55554
Uniprot:Q9H2R5
Cellular Location:Secreted
Calculated MW:13kDa/17kDa/19kDa/28kDa
Observed MW:28kDa
Synonyms:KLK15, ACO, HSRNASPH
Background:Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.
UniProt Protein Function:Protease whose physiological substrate is not yet known.
NCBI Summary:Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
UniProt Code:Q9H2R5
NCBI GenInfo Identifier:18202940
NCBI Gene ID:55554
NCBI Accession:Q9H2R5.1
UniProt Secondary Accession:Q9H2R5,Q15358, Q6ISI0, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9 A0AUY8,
UniProt Related Accession:Q9H2R5
Molecular Weight:
NCBI Full Name:Kallikrein-15
NCBI Synonym Full Names:kallikrein related peptidase 15
NCBI Official Symbol:KLK15  
NCBI Official Synonym Symbols:ACO; HSRNASPH  
NCBI Protein Information:kallikrein-15
UniProt Protein Name:Kallikrein-15
UniProt Synonym Protein Names:ACO protease
Protein Family:Kallikrein
UniProt Gene Name:KLK15  
Anti-KLK15 Antibody (CAB2757)Western blot analysis of extracts of various cell lines, using KLK15 antibody (CAB2757) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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