Cell Biology Antibodies 5
Anti-KLHL1 Antibody (CAB14594)
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- SKU:
- CAB14594
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-KLHL1 Antibody |
| Antibody SKU: | CAB14594 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human KLHL1 (NP_065917.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | A-431 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human KLHL1 (NP_065917.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSGS GRKD FDVK HILR LRWK LFSH PSPS TGGP AGGG CLQQ DGSG SFEH WGPS QSRL LKSQ ERSG VSTF WKKP SSSS SSSS SPSS SSSS FNPL NGTL LPVA TRLQ QGAP GQGT QQPA RTLF YVES LEEE VVPG MDFP GPHE KGLV LQEL KVEP DNSS QATG EGCG HRLS STGH SMTP QSDL DSSS SEEF YQAV HHAE QTFR KMES YLKQ QQ |
| Gene ID: | 57626 |
| Uniprot: | Q9NR64 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 82kDa |
| Observed MW: | 83kDa |
| Synonyms: | KLHL1, MRP2 |
| Background: |
| UniProt Protein Function: | KLHL1: May play a role in organizing the actin cytoskeleton of the brain cells. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 13q21 Cellular Component: cell soma; cytoplasm; dendrite Molecular Function:ubiquitin-protein ligase activity Biological Process: dendrite development |
| NCBI Summary: | The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).[supplied by OMIM, Feb 2010] |
| UniProt Code: | Q9NR64 |
| NCBI GenInfo Identifier: | 13431647 |
| NCBI Gene ID: | 57626 |
| NCBI Accession: | Q9NR64.1 |
| UniProt Secondary Accession: | Q9NR64,Q5VZ64, Q9H4X4, Q9NR65, Q9P238, A8K5X0, |
| UniProt Related Accession: | Q9NR64 |
| Molecular Weight: | 82,680 Da |
| NCBI Full Name: | Kelch-like protein 1 |
| NCBI Synonym Full Names: | kelch like family member 1 |
| NCBI Official Symbol: | KLHL1 |
| NCBI Official Synonym Symbols: | MRP2 |
| NCBI Protein Information: | kelch-like protein 1 |
| UniProt Protein Name: | Kelch-like protein 1 |
| Protein Family: | Kelch-like protein |
| UniProt Gene Name: | KLHL1 |
| UniProt Entry Name: | KLHL1_HUMAN |
 | Western blot analysis of extracts of A-431 cells, using KLHL1 antibody (CAB14594) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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