Cell Biology Antibodies 4
Anti-KLC3 Antibody (CAB14341)
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- SKU:
- CAB14341
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-KLC3 Antibody |
| Antibody SKU: | CAB14341 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human KLC3 (NP_803136.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse brain, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human KLC3 (NP_803136.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSVQ VAAP GSAG LGPE RLSP EELV RQTR QVVQ GLEA LRAE HHGL AGHL AEAL AGQG PAAG LEML EEKQ QVVS HSLE AIEL GLGE AQVL LALS AHVG ALEA EKQR LRSQ ARRL AQEN VWLR EELE ETQR RLRA SEE |
| Gene ID: | 147700 |
| Uniprot: | Q6P597 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 55kDa/56kDa |
| Observed MW: | 55kDa |
| Synonyms: | KLC3, KLC2, KLC2L, KLCt, KNS2B |
| Background: | This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. |
| NCBI Summary: | This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q6P597 |
| NCBI GenInfo Identifier: | 91825557 |
| NCBI Gene ID: | 147700 |
| NCBI Accession: | NP_803136 |
| UniProt Related Accession: | Q6P597 |
| Molecular Weight: | 55kDa |
| NCBI Full Name: | kinesin light chain 3 |
| NCBI Synonym Full Names: | kinesin light chain 3 |
| NCBI Official Symbol: | KLC3 |
| NCBI Official Synonym Symbols: | KLC2; KLCt; KLC2L; KNS2B |
| NCBI Protein Information: | kinesin light chain 3 |
| UniProt Protein Name: | Kinesin light chain 3 |
| UniProt Synonym Protein Names: | KLC2-like; kinesin light chain 2 |
| Protein Family: | Kinesin |
| UniProt Gene Name: | KLC3 |
| UniProt Entry Name: | KLC3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using KLC3 antibody (CAB14341) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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