Cell Biology Antibodies 11

Anti-KIF6 Antibody (CAB7614)

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SKU:
CAB7614
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-KIF6 Antibody
Antibody SKU:CAB7614
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 565-814 of human KIF6 (NP_659464.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 565-814 of human KIF6 (NP_659464.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FKRD HADS VTID DNKQ ILKQ RFSE AKAL GESI NEAR SKIG HLKE EITQ RHIQ QVAL GISE NMAV PLMP DQQE EKLR SQLE EEKR RYKT MFTR LKAL KVEI EHLQ LLMD KAKV KLQK EFEV WWAE EATN LQVN SPAV NSLD HTKP FLQT SDSQ HEWS QLLS NKSS GGWE VQDQ GTGR FDVC DVNA RKIL PSPC PSPH SQKQ SSTS TPLE DSIP KRPV SSIP LTGD SQTD SDII AFIK ARQS ILQK QCLG SN
Gene ID:221458
Uniprot:Q6ZMV9
Cellular Location:Cytoplasm, cytoskeleton
Calculated MW:19kDa/30kDa/90kDa/92kDa
Observed MW:93kDa
Synonyms:KIF6, C6orf102, dJ1043E3.1, dJ137F1.4, dJ188D3.1
Background:
UniProt Protein Function:KIF6: Belongs to the kinesin-like protein family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Motor; Microtubule-binding

Chromosomal Location of Human Ortholog: 6p21.2

Cellular Component: male germ cell nucleus; microtubule; kinesin complex; cytoplasm

Molecular Function:protein binding; microtubule binding; ATPase activity; microtubule motor activity; ATP binding

Biological Process: metabolic process; microtubule-based movement

NCBI Summary:This gene encodes a member of a family of molecular motors which are involved in intracellular transport of protein complexes, membrane organelles, and messenger ribonucleic acid along microtubules. Kinesins function as homodimeric molecules with two N-terminal head domains that move along microtubules and two C-terminal tail domains that interact with the transported cargo, either directly or indirectly, through adapter molecules. This gene is ubiquitously expressed in coronary arteries and other vascular tissue. A naturally occurring mutation in this gene is associated with coronary heart disease. [provided by RefSeq, May 2017]
UniProt Code:Q6ZMV9
NCBI GenInfo Identifier:146345445
NCBI Gene ID:221458
NCBI Accession:Q6ZMV9.3
UniProt Related Accession:Q6ZMV9
Molecular Weight:19kDa; 30kDa; 90kDa; 92kDa
NCBI Full Name:Kinesin-like protein KIF6
NCBI Synonym Full Names:kinesin family member 6
NCBI Official Symbol:KIF6  
NCBI Official Synonym Symbols:C6orf102; dJ137F1.4; dJ188D3.1; dJ1043E3.1  
NCBI Protein Information:kinesin-like protein KIF6
UniProt Protein Name:Kinesin-like protein KIF6
Protein Family:Kinesin-like protein
UniProt Gene Name:KIF6  
UniProt Entry Name:KIF6_HUMAN
Anti-KIF6 Antibody (CAB7614)Western blot analysis of extracts of mouse testis, using KIF6 antibody (CAB7614) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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