Anti-KIF4A Antibody (CAB9080)
- SKU:
- CAB9080
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KIF4
- Synonyms:
- KIF4G1
- Synonyms:
- MRX100
- Research Area:
- Cell Biology
Description
| Product Name: | KIF4A Rabbit mAb |
| Product Code: | CAB9080 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | KIF4, KIF4G1, MRX100 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human KIF4A |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, A-549 |
| Immunogen: | A synthesized peptide derived from human KIF4A |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 24137 |
| Uniprot: | O95239 |
| Calculated MW: | 150kDa |
| Observed MW: | 160KDa |
| UniProt Protein Function: | KIF4A: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. Belongs to the kinesin-like protein family. Chromokinesin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Microtubule-binding; Motor Chromosomal Location of Human Ortholog: Xq13.1 Cellular Component: cytoplasm; cytosol; intercellular bridge; kinesin complex; membrane; midbody; nucleoplasm; spindle microtubule Molecular Function:microtubule motor activity; plus-end-directed microtubule motor activity; protein binding Biological Process: anterograde axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; cytokinesis after mitosis; microtubule-based movement; organelle organization and biogenesis; retrograde vesicle-mediated transport, Golgi to ER; spindle midzone assembly involved in mitosis Disease: Mental Retardation, X-linked 100 |
| NCBI Summary: | This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010] |
| UniProt Code: | O95239 |
| NCBI GenInfo Identifier: | 62512161 |
| NCBI Gene ID: | 24137 |
| NCBI Accession: | O95239.3 |
| UniProt Secondary Accession: | O95239,Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3, B2R7V5 D3DVU4, |
| UniProt Related Accession: | O95239 |
| Molecular Weight: | 140kDa |
| NCBI Full Name: | Chromosome-associated kinesin KIF4A |
| NCBI Synonym Full Names: | kinesin family member 4A |
| NCBI Official Symbol: | KIF4A |
| NCBI Official Synonym Symbols: | KIF4; KIF4G1; MRX100 |
| NCBI Protein Information: | chromosome-associated kinesin KIF4A |
| UniProt Protein Name: | Chromosome-associated kinesin KIF4A |
| UniProt Synonym Protein Names: | Chromokinesin-A |
| Protein Family: | Chromosome-associated kinesin |
| UniProt Gene Name: | KIF4A |
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