Cell Cycle Antibodies 1
Anti-KIF2B Antibody (CAB6480)
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- SKU:
- CAB6480
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
| Antibody Name: | Anti-KIF2B Antibody |
| Antibody SKU: | CAB6480 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 544-673 of human KIF2B (NP_115948.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-937, Mouse lung, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 544-673 of human KIF2B (NP_115948.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NVDV RPYH RGHY PIGH EAPR MLKS HIGN SEMS LQRD EFIK IPYV QSEE QKEI EEVE TLPT LLGK DTTI SGKG SSQW LENI QERA GGVH HDID FCIA RSLS ILEQ KIDA LTEI QKKL KLLL ADLH VKSK VE |
| Gene ID: | 84643 |
| Uniprot: | Q8N4N8 |
| Cellular Location: | Chromosome, Cytoplasm, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle |
| Calculated MW: | 76kDa |
| Observed MW: | 76kDa |
| Synonyms: | KIF2B |
| Background: |
| UniProt Protein Function: | KIF2B: Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily. |
| UniProt Protein Details: | Protein type:Motor; Microtubule-binding Chromosomal Location of Human Ortholog: 17q22 Cellular Component: microtubule cytoskeleton; kinesin complex; microtubule; nucleolus; microtubule organizing center; spindle; cytosol; nucleus Molecular Function:microtubule binding; ATPase activity; microtubule motor activity; ATP binding Biological Process: mitosis; cell division; metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class II; microtubule depolymerization; regulation of chromosome segregation; mitotic cell cycle; blood coagulation; microtubule-based movement |
| UniProt Code: | Q8N4N8 |
| NCBI GenInfo Identifier: | 308153588 |
| NCBI Gene ID: | 84643 |
| NCBI Accession: | Q8N4N8.3 |
| UniProt Secondary Accession: | Q8N4N8,Q96MA2, Q9BXG6, |
| UniProt Related Accession: | Q8N4N8 |
| Molecular Weight: | 673 |
| NCBI Full Name: | Kinesin-like protein KIF2B |
| NCBI Synonym Full Names: | kinesin family member 2B |
| NCBI Official Symbol: | KIF2B |
| NCBI Protein Information: | kinesin-like protein KIF2B; kinesin protein |
| UniProt Protein Name: | Kinesin-like protein KIF2B |
| Protein Family: | Kinesin-like protein |
| UniProt Gene Name: | KIF2B |
| UniProt Entry Name: | KIF2B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using KIF2B antibody (CAB6480) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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