Cell Cycle Antibodies 1
Anti-KIF23 Antibody (CAB10800)
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- SKU:
- CAB10800
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
| Antibody Name: | Anti-KIF23 Antibody |
| Antibody SKU: | CAB10800 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human KIF23 (NP_612565.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Raji, 293T, B cells, NCI-H460, HeLa, Mouse kidney, Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human KIF23 (NP_612565.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NGQQ LMSQ PQLH RRSN SCSS ISVA SCIS EWEQ KIPT YNTP LKVT SIAR RRQQ EPGQ SKTC IVSD RRRG MYWT EGRE VVPT FRNE IEIE EDHC GRLL FQPD QNAP PIRL RHRR SRSA GDRW VDHK PASN MQTE TVMQ PHVP HAIT VSVA NEKA LAKC EKYM LTHQ ELAS DGEI ETKL IKGD IYKT RGGG QSVQ FTDI ETLK QESP NGSR KRRS STVA PAQP DGAE SEWT DVET RCSV AVEM RAGS QLGP GYQ |
| Gene ID: | 9493 |
| Uniprot: | Q02241 |
| Cellular Location: | Cytoplasm, Midbody, Nucleus, cytoskeleton, spindle |
| Calculated MW: | 77kDa/98kDa/110kDa |
| Observed MW: | 110kDa |
| Synonyms: | KIF23, CHO1, KNSL5, MKLP-1, MKLP1 |
| Background: | The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. |
| UniProt Protein Function: | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. |
| NCBI Summary: | The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q02241 |
| NCBI GenInfo Identifier: | 118572664 |
| NCBI Gene ID: | 9493 |
| NCBI Accession: | Q02241.3 |
| UniProt Secondary Accession: | Q02241,Q8WVP0, B4E1K0, |
| UniProt Related Accession: | Q02241 |
| Molecular Weight: | 110kDa |
| NCBI Full Name: | Kinesin-like protein KIF23 |
| NCBI Synonym Full Names: | kinesin family member 23 |
| NCBI Official Symbol: | KIF23 |
| NCBI Official Synonym Symbols: | CHO1; KNSL5; MKLP1; MKLP-1 |
| NCBI Protein Information: | kinesin-like protein KIF23 |
| UniProt Protein Name: | Kinesin-like protein KIF23 |
| UniProt Synonym Protein Names: | Kinesin-like protein 5; Mitotic kinesin-like protein 1 |
| Protein Family: | Kinesin-like protein |
| UniProt Gene Name: | KIF23 |
 | Western blot analysis of extracts of various cell lines, using KIF23 antibody (CAB10800) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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