Cell Cycle Antibodies 1

Anti-KIF20B Antibody (CAB15360)

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SKU:
CAB15360
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle

Description

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Antibody Name:Anti-KIF20B Antibody
Antibody SKU:CAB15360
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2).
Application:WB IF
Recommended Dilution:WB 1:200 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, OVCAR3, 293T, HT-29, NIH/3T3, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KHLL QLKE EEEE TNRQ ETEK LKEE LSAS SART QNLK ADLQ RKEE DYAD LKEK LTDA KKQI KQVQ KEVS VMRD EDKL LRIK INEL EKKK NQCS QELD MKQR TIQQ LKEQ LNNQ KVEE AIQQ YERA CKDL NVKE KIIE DMRM TLEE QEQT QVEQ DQVL EAKL EEVE RLAT ELEK WKEK CNDL ETKN NQRS NKEH ENNT DVLG KLTN LQDE LQES EQKY NADR KKWL EEKM MLIT QAKE AENI RNKE MKKY AEDR ERFF KQQN EMEI LTAQ LTEK DSDL QKWR EERD QLVA ALEI QLKA LISS N
Gene ID:9585
Uniprot:Q96Q89
Cellular Location:Cell projection, Cytoplasm, Midbody, Nucleus, axon, centrosome, cytoskeleton, growth cone, microtubule organizing center, nucleolus, nucleoplasm, spindle, spindle pole
Calculated MW:59kDa/199kDa/206kDa/210kDa/214kDa
Observed MW:210kDa
Synonyms:KIF20B, CT90, KRMP1, MPHOSPH1, MPP-1, MPP1
Background:
UniProt Protein Function:Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).
UniProt Code:Q96Q89
NCBI GenInfo Identifier:546231677
NCBI Gene ID:9585
NCBI Accession:NP_001271188.1
UniProt Secondary Accession:Q96Q89,O43277, Q09471, Q2KQ73, Q32NE1, Q561V3, Q58EX8 Q5T9M8, Q5T9M9, Q5T9N0, Q5T9N1, A8MXM7,
UniProt Related Accession:Q96Q89
Molecular Weight:59,621 Da
NCBI Full Name:kinesin-like protein KIF20B isoform 1
NCBI Synonym Full Names:kinesin family member 20B
NCBI Official Symbol:KIF20B  
NCBI Official Synonym Symbols:CT90; MPP1; KRMP1; MPP-1; MPHOSPH1  
NCBI Protein Information:kinesin-like protein KIF20B
UniProt Protein Name:Kinesin-like protein KIF20B
UniProt Synonym Protein Names:Cancer/testis antigen 90; CT90; Kinesin family member 20B
Protein Family:Mitochondrial-processing peptidase
UniProt Gene Name:KIF20B  
Anti-KIF20B Antibody (CAB15360)Western blot analysis of extracts of various cell lines, using KIF20B antibody (CAB15360) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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