Cell Biology Antibodies 6

Anti-KIF1C Antibody (CAB15786)

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SKU:
CAB15786
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-KIF1C Antibody
Antibody SKU:CAB15786
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 810-960 of human KIF1C (NP_006603.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, HepG2, 293T, K-562, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 810-960 of human KIF1C (NP_006603.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:EEGG GAGS GGGS EEGA RGAE VEDL RAHI DKLT GILQ EVKL QNSS KDRE LQAL RDRM LRME RVIP LAQD HEDE NEEG GEVP WAPP EGSE AAEE AAPS DRMP SARP PSPP LSSW ERVS RLME EDPA FRRG RLRW LKQE QLRL QGLQ GSGG RGG
Gene ID:10749
Uniprot:O43896
Cellular Location:Cytoplasm, cytoskeleton
Calculated MW:122kDa
Observed MW:165kDa
Synonyms:KIF1C, LTXS1, SATX2, SAX2, SPAX2, SPG58
Background:The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive.
UniProt Protein Function:KIF1C: Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end- directed motility. Belongs to the kinesin-like protein family. Unc-104 subfamily.
UniProt Protein Details:

Protein type:Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: endoplasmic reticulum; kinesin complex

Molecular Function:ATPase activity; microtubule motor activity; motor activity; protein binding

Biological Process: cytoskeleton-dependent intracellular transport; microtubule-based movement

Disease: Spastic Ataxia 2, Autosomal Recessive

NCBI Summary:The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive. [provided by RefSeq, May 2014]
UniProt Code:O43896
NCBI GenInfo Identifier:40254834
NCBI Gene ID:10749
NCBI Accession:NP_006603.2
UniProt Secondary Accession:O43896,O75186, Q5U618, D3DTL6,
UniProt Related Accession:O43896
Molecular Weight:122,947 Da
NCBI Full Name:kinesin-like protein KIF1C
NCBI Synonym Full Names:kinesin family member 1C
NCBI Official Symbol:KIF1C  
NCBI Official Synonym Symbols:SAX2; LTXS1; SATX2; SPAX2; SPG58  
NCBI Protein Information:kinesin-like protein KIF1C
UniProt Protein Name:Kinesin-like protein KIF1C
Protein Family:Kinesin-like protein
UniProt Gene Name:KIF1C  
Anti-KIF1C Antibody (CAB15786)Western blot analysis of extracts of various cell lines, using KIF1C antibody (CAB15786) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
Anti-KIF1C Antibody (CAB15786)Immunohistochemistry of paraffin-embedded rat heart using KIF1C antibody (CAB15786) at dilution of 1:100 (40x lens).
Anti-KIF1C Antibody (CAB15786)Immunohistochemistry of paraffin-embedded mouse heart using KIF1C antibody (CAB15786) at dilution of 1:100 (40x lens).
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