Autophagy Antibodies

Anti-KIAA1324 Antibody (CAB15490)

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SKU:
CAB15490
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy

Description

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Antibody Name:Anti-KIAA1324 Antibody
Antibody SKU:CAB15490
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 42-300 of human KIAA1324 (NP_001253977.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 42-300 of human KIAA1324 (NP_001253977.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TGPE LHAC KESE YHYE YTAC DSTG SRWR VAVP HTPG LCTS LPDP VKGT ECSF SCNA GEFL DMKD QSCK PCAE GRYS LGTG IRFD EWDE LPHG FASL SANM ELDD SAAE STGN CTSS KWVP RGDY IASN TDEC TATL MYAV NLKQ SGTV NFEY YYPD SSII FEFF VQND QCQP NADD SRWM KTTE KGWE FHSV ELNR GNNV LYWR TTAF SVWT KVPK PVLT QLMY KWAK PKIC SEDL EGAV KLPA SGVK THCP PCNP GFF
Gene ID:57535
Uniprot:Q6UXG2
Cellular Location:Cell membrane, Golgi apparatus, Late endosome membrane, Lysosome membrane, Single-pass membrane protein, Single-pass type I membrane protein, trans-Golgi network membrane
Calculated MW:101kDa/109kDa/110kDa/111kDa
Observed MW:Refer to figures
Synonyms:KIAA1324, EIG121
Background:Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants.
UniProt Protein Function:KIAA1324: May play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. Belongs to the UPF0577 family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: late endosome membrane; lysosome; integral to plasma membrane; lysosomal membrane; late endosome; trans-Golgi network

Biological Process: macroautophagy; cellular response to starvation

NCBI Summary:Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
UniProt Code:Q6UXG2
NCBI GenInfo Identifier:38569482
NCBI Gene ID:57535
NCBI Accession:NP_065826.2
UniProt Secondary Accession:Q6UXG2,Q08AE6, Q5T5C9, Q5T5D0, Q5T5D1, Q9P2M2,
UniProt Related Accession:Q6UXG2
Molecular Weight:110,416 Da
NCBI Full Name:UPF0577 protein KIAA1324 isoform 1
NCBI Synonym Full Names:KIAA1324
NCBI Official Symbol:KIAA1324  
NCBI Official Synonym Symbols:EIG121  
NCBI Protein Information:UPF0577 protein KIAA1324; maba1; estrogen-induced gene 121 protein
UniProt Protein Name:UPF0577 protein KIAA1324
UniProt Synonym Protein Names:Estrogen-induced gene 121 protein
UniProt Gene Name:KIAA1324  
UniProt Entry Name:K1324_HUMAN
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