Anti-KDM3B Antibody (CAB2312)
- SKU:
- CAB2312
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KDM3B
- Synonyms:
- 5qNCA
- Synonyms:
- C5orf7
- Synonyms:
- JMJD1B
- Synonyms:
- NET22
Description
| Product Name: | KDM3B Rabbit pAb |
| Product Code: | CAB2312 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | KDM3B, 5qNCA, C5orf7, JMJD1B, NET22 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1059-1283 of human KDM3B (NP_057688.2). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1059-1283 of human KDM3B (NP_057688.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LRKS RPRS ETEE MGDE EVFS WLKC AKGQ SHEP ENLM PTQI IPGT ALYN IGDM VHAA RGKW GIKA NCPC ISRQ NKSV LRPA VTNG MSQL PSIN PSAS SGNE TTFS GGGG PAPV TTPE PDHV PKAD STDI RSEE PLKT DSSA SNSN SELK AIRP PCPD TAPP SSAL HWLA DLAT QKAK EETK EAGS LRSV LNKE SHSP FGLD SFNS TAKV SPLT PKLF NSLL LGPT A |
| Gene ID: | 51780 |
| Uniprot: | Q7LBC6 |
| Cellular Location: | Nucleus |
| Calculated MW: | 84kDa/154kDa/191kDa |
| Observed MW: | 225KDa |
| UniProt Protein Function: | JMJD1B: a ubiquitous protein demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. Three alternatively spliced isoforms have been reported. Protein type: EC 1.14.11.-; Oxidoreductase; Demethylase Chromosomal Location of Human Ortholog: 5q31 Cellular Component: nucleoplasm Molecular Function: dioxygenase activity; metal ion binding Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent; transcription, DNA-dependent; chromatin modification |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q7LBC6 |
| NCBI GenInfo Identifier: | 308153456 |
| NCBI Gene ID: | 51780 |
| NCBI Accession: | Q7LBC6.2 |
| UniProt Secondary Accession: | Q7LBC6 |
| UniProt Related Accession: | Q7LBC6 |
| Molecular Weight: | Predicted MW: 29.2kDaAccurate MW: 29kDa |
| NCBI Full Name: | Lysine-specific demethylase 3B |
| NCBI Synonym Full Names: | lysine demethylase 3B |
| NCBI Official Symbol: | KDM3B |
| NCBI Official Synonym Symbols: | 5qNCA; NET22; C5orf7; JMJD1B |
| NCBI Protein Information: | lysine-specific demethylase 3B |
| UniProt Protein Name: | Lysine-specific demethylase 3B |
| UniProt Synonym Protein Names: | JmjC domain-containing histone demethylation protein 2B; Jumonji domain-containing protein 1B; Nuclear protein 5qNCA |
| Protein Family: | Lysine-specific demethylase |
| UniProt Gene Name: | KDM3B |
| UniProt Entry Name: | KDM3B_HUMAN |
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