Signal Transduction Antibodies 3

Anti-KCNJ9 Antibody (CAB9825)

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SKU:
CAB9825
Product Type:
Antibody
Applications:
WB
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-KCNJ9 Antibody
Antibody SKU:CAB9825
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KCNJ9 (NP_004974.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KCNJ9 (NP_004974.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAQE NAAF SPGQ EEPP RRRG RQRY VEKD GRCN VQQG NVRE TYRY LTDL FTTL VDLQ WRLS LLFF VLAY ALTW LFFG AIWW LIAY GRGD LEHL EDTA WTPC
Gene ID:3765
Uniprot:Q92806
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:44kDa
Observed MW:Refer to figures
Synonyms:KCNJ9, GIRK3, KIR3.3
Background:Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex.
UniProt Protein Function:GIRK3: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ9 subfamily.
UniProt Protein Details:

Protein type:Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function:G-protein activated inward rectifier potassium channel activity; inward rectifier potassium channel activity; protein binding

Biological Process: potassium ion import

NCBI Summary:Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]
UniProt Code:Q92806
NCBI GenInfo Identifier:125987834
NCBI Gene ID:3765
NCBI Accession:Q92806.2
UniProt Secondary Accession:Q92806,Q5JW75,
UniProt Related Accession:Q92806
Molecular Weight:44kDa
NCBI Full Name:G protein-activated inward rectifier potassium channel 3
NCBI Synonym Full Names:potassium voltage-gated channel subfamily J member 9
NCBI Official Symbol:KCNJ9  
NCBI Official Synonym Symbols:GIRK3; KIR3.3  
NCBI Protein Information:G protein-activated inward rectifier potassium channel 3
UniProt Protein Name:G protein-activated inward rectifier potassium channel 3
UniProt Synonym Protein Names:Inward rectifier K(+) channel Kir3.3; Potassium channel, inwardly rectifying subfamily J member 9
Protein Family:G protein-activated inward rectifier potassium channel
UniProt Gene Name:KCNJ9  
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