Anti-KAT9/Elp3 Antibody (CAB0020)
- SKU:
- CAB0020
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KAT9
- Research Area:
- Neuroscience
Description
| Product Name: | KAT9/Elp3 Rabbit mAb |
| Product Code: | CAB0020 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | KAT9 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human KAT9/Elp3 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, K-562, SH-SY5Y, Mouse testis, Mouse brain, Mouse kidney, Rat lung, Rat testis, Rat brain |
| Immunogen: | A synthesized peptide derived from human KAT9/Elp3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 55140 |
| Uniprot: | Q9H9T3 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 62kDa |
| Observed MW: | 62kDa |
| UniProt Protein Function: | ELP3: a histone acetyltransferase. A subunit of the Elongator complex, which associates with the elongating, hyperphosphorylated form of RNA polymerase II. |
| UniProt Protein Details: | Protein type:EC 2.3.1.48; Acetyltransferase Chromosomal Location of Human Ortholog: 8p21.1 Cellular Component: cytoplasm; Elongator holoenzyme complex; histone acetyltransferase complex; nucleolus; transcription elongation factor complex Molecular Function:H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; phosphorylase kinase regulator activity; protein binding Biological Process: central nervous system development; neuron migration; positive regulation of cell migration; regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter; tRNA wobble uridine modification |
| NCBI Summary: | ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009] |
| UniProt Code: | Q9H9T3 |
| NCBI GenInfo Identifier: | 145558902 |
| NCBI Gene ID: | 55140 |
| NCBI Accession: | Q9H9T3.2 |
| UniProt Secondary Accession: | Q9H9T3,Q53G84, Q6AWB0, Q9BVF7, Q9NVZ1, B4DE19, B4DIG1 E2QRI5, |
| UniProt Related Accession: | Q9H9T3 |
| Molecular Weight: | 52,202 Da |
| NCBI Full Name: | Elongator complex protein 3 |
| NCBI Synonym Full Names: | elongator acetyltransferase complex subunit 3 |
| NCBI Official Symbol: | ELP3 |
| NCBI Official Synonym Symbols: | KAT9 |
| NCBI Protein Information: | elongator complex protein 3 |
| UniProt Protein Name: | Elongator complex protein 3 |
| Protein Family: | Elongator complex protein |
| UniProt Gene Name: | ELP3 |
| UniProt Entry Name: | ELP3_HUMAN |
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