Cell Biology Antibodies 17
Anti-K Cadherin Antibody (CAB4689)
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- SKU:
- CAB4689
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-K Cadherin Antibody |
| Antibody SKU: | CAB4689 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human K Cadherin |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HepG2, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human K Cadherin |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1004 |
| Uniprot: | P55285 |
| Cellular Location: | |
| Calculated MW: | 130kDa |
| Observed MW: | 130KDa |
| Synonyms: | CAD6, KCAD |
| Background: | This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011] |
| UniProt Protein Function: | CDH6: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 5p13.3 Cellular Component: plasma membrane; integral to membrane Molecular Function:calcium ion binding Biological Process: intercellular junction assembly and maintenance; homophilic cell adhesion; cell adhesion |
| NCBI Summary: | This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011] |
| UniProt Code: | P55285 |
| NCBI GenInfo Identifier: | 1705545 |
| NCBI Gene ID: | 1004 |
| NCBI Accession: | P55285.1 |
| UniProt Secondary Accession: | P55285,Q9BWS0, A8K5H5, |
| UniProt Related Accession: | P55285 |
| Molecular Weight: | 73,864 Da |
| NCBI Full Name: | Cadherin-6 |
| NCBI Synonym Full Names: | cadherin 6, type 2, K-cadherin (fetal kidney) |
| NCBI Official Symbol: | CDH6 |
| NCBI Official Synonym Symbols: | CAD6; KCAD |
| NCBI Protein Information: | cadherin-6 |
| UniProt Protein Name: | Cadherin-6 |
| UniProt Synonym Protein Names: | Kidney cadherin; K-cadherin |
| Protein Family: | Cadherin |
| UniProt Gene Name: | CDH6 |
| UniProt Entry Name: | CADH6_HUMAN |
 | Western blot - K Cadherin Rabbit mAb (CAB4689) |
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