Cell Biology Antibodies 17
Anti-JPH1 Antibody (CAB18476)
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- SKU:
- CAB18476
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-JPH1 Antibody |
| Antibody SKU: | CAB18476 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human JPH1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse skeletal muscle |
| Immunogen: | Recombinant protein of human JPH1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 56704 |
| Uniprot: | Q9HDC5 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 62kDa |
 | Western blot - JPH1 Rabbit pAb (CAB18476) |
| Synonyms: | CMT2K, JP-1, JP1, JPH1 |
| Background: |
| UniProt Protein Function: | JPH1: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes. Belongs to the junctophilin family. |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum; Membrane protein, integral Chromosomal Location of Human Ortholog: 8q21 Cellular Component: junctional membrane complex; plasma membrane; integral to membrane; Z disc Molecular Function:structural constituent of muscle Biological Process: muscle development |
| NCBI Summary: | Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HDC5 |
| NCBI GenInfo Identifier: | 145337941 |
| NCBI Gene ID: | 56704 |
| NCBI Accession: | AAI39833 |
| UniProt Secondary Accession: | Q9HDC5,B2RTZ0, |
| UniProt Related Accession: | Q9HDC5 |
| Molecular Weight: | 71,686 Da |
| NCBI Full Name: | JPH1 protein, partial |
| NCBI Synonym Full Names: | junctophilin 1 |
| NCBI Official Symbol: | JPH1 |
| NCBI Official Synonym Symbols: | JP1; JP-1 |
| NCBI Protein Information: | junctophilin-1; mitsugumin72; junctophilin type1; junctophilin type 1 |
| UniProt Protein Name: | Junctophilin-1 |
| UniProt Synonym Protein Names: | Junctophilin type 1 |
| Protein Family: | Junctophilin |
| UniProt Gene Name: | JPH1 |
| UniProt Entry Name: | JPH1_HUMAN |
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