Epigenetics & Nuclear Signaling Antibodies 2
Anti-JDP2 Antibody (CAB15208)
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- SKU:
- CAB15208
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-JDP2 Antibody |
| Antibody SKU: | CAB15208 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human JDP2 (NP_001128521.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa, Jurkat, HepG2, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human JDP2 (NP_001128521.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVAG WPAT PPAM MPGQ IPDP SVTT GSLP GLGP LTGL PSSA LTVE ELKY ADIR NLGA MIAP LHFL EVKL GKRP QPVK SELD EEEE RRKR RREK NKVA AARC RNKK KERT EFLQ RESE RLEL MNAE LKTQ IEEL KQER QQLI LMLN RHRP TCIV RTDS VKTP ESEG NPLL EQLE KK |
| Gene ID: | 122953 |
| Uniprot: | Q8WYK2 |
| Cellular Location: | Nucleus |
| Calculated MW: | 18kDa/19kDa |
| Observed MW: | 18kDa |
| Synonyms: | JDP2, JUNDM2 |
| Background: |
| UniProt Protein Function: | JDP2: a transcriptional coregulator that may play a role in progesterone receptor signaling. a JDP-2 lacks an intrinsic activation domain and interacts directly with other coactivators including CBP and pCAF. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 14q24.3 Cellular Component: nucleus Molecular Function:chromatin binding; protein binding; protein heterodimerization activity Biological Process: negative regulation of fat cell differentiation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone deacetylation; transcription, DNA-dependent |
| UniProt Code: | Q8WYK2 |
| NCBI GenInfo Identifier: | 205277421 |
| NCBI Gene ID: | 122953 |
| NCBI Accession: | NP_001128521.1 |
| UniProt Secondary Accession: | Q8WYK2,O95430, Q9UIE4, J3KN58, |
| UniProt Related Accession: | Q8WYK2 |
| Molecular Weight: | Calculated MW: 19Observed MW: 22 |
| NCBI Full Name: | jun dimerization protein 2 isoform b |
| NCBI Synonym Full Names: | Jun dimerization protein 2 |
| NCBI Official Symbol: | JDP2 |
| NCBI Official Synonym Symbols: | JUNDM2 |
| NCBI Protein Information: | jun dimerization protein 2 |
| UniProt Protein Name: | Jun dimerization protein 2 |
| Protein Family: | Jun dimerization protein |
| UniProt Gene Name: | JDP2 |
| UniProt Entry Name: | JDP2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using JDP2 antibody (CAB15208) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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