Cell Biology Antibodies 4

Anti-JAKMIP1 Antibody (CAB13774)

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SKU:
CAB13774
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-JAKMIP1 Antibody
Antibody SKU:CAB13774
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 337-626 of human JAKMIP1 (NP_653321.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, Mouse brain, Mouse spleen, Mouse testis, Rat brain, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 337-626 of human JAKMIP1 (NP_653321.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KRMN KKNE DLLQ SIQR MEEK IKNL TREN VEMK EKLS AQAS LKRH TSLN DLSL TRDE QEIE FLRL QVLE QQHV IDDL SLER ERLL RSKR HRGK SLKP PKKH VVET FFGF DEES VDSE TLSE TSYN TDRT DRTP ATPE EDLD DATA REEA DLRF CQLT REYQ ALQR AYAL LQEQ VGGT LDAE REAR TREQ LQAD LLRC QAKI EDLE KLLV EKGQ DSKW VEEK QLLI RTNQ DLLE KIYR LEME ENQL KNEM QDAK DQNE LLEF RVLE LEVR DSIC CKLS NGAD ILFE PKLK FM
Gene ID:152789
Uniprot:Q96N16
Cellular Location:Cytoplasm, Membrane, Peripheral membrane protein, cytoskeleton
Calculated MW:45kDa/49kDa/53kDa/67kDa/73kDa/75kDa/97kDa
Observed MW:73kDa
Synonyms:JAKMIP1, Gababrbp, JAMIP1, MARLIN1
Background:
UniProt Protein Function:JAKMIP1: Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. Belongs to the JAKMIP family. 6 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:RNA-binding

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: microtubule; extrinsic to membrane; cytoplasm; ribonucleoprotein complex

Molecular Function:protein binding; RNA binding; kinesin binding; microtubule binding; GABA receptor binding; kinase binding

Biological Process: protein transport; cognition

UniProt Code:Q96N16
NCBI GenInfo Identifier:74732477
NCBI Gene ID:152789
NCBI Accession:Q96N16.1
UniProt Secondary Accession:Q96N16,Q86Y69, Q8N7G3, A6H2J2, A6H2J3, A6H2J4, A6H2J5 A8MTK6, B4DHZ8, B8ZZR7, D3DVT0,
UniProt Related Accession:Q96N16
Molecular Weight:626
NCBI Full Name:Janus kinase and microtubule-interacting protein 1
NCBI Synonym Full Names:janus kinase and microtubule interacting protein 1
NCBI Official Symbol:JAKMIP1  
NCBI Official Synonym Symbols:JAMIP1; MARLIN1; Gababrbp  
NCBI Protein Information:janus kinase and microtubule-interacting protein 1; marlin-1; GABA-B receptor-binding protein; Jak and microtubule interacting protein 1; multiple coiled-coil GABABR1-binding protein; multiple alpha-helices and RNA-linker protein 1
UniProt Protein Name:Janus kinase and microtubule-interacting protein 1
UniProt Synonym Protein Names:GABA-B receptor-binding protein; Multiple alpha-helices and RNA-linker protein 1; Marlin-1
Protein Family:Janus kinase and microtubule-interacting protein
UniProt Gene Name:JAKMIP1  
UniProt Entry Name:JKIP1_HUMAN
Anti-JAKMIP1 Antibody (CAB13774)Western blot analysis of extracts of various cell lines, using JAKMIP1 antibody (CAB13774) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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