Anti-IZUMO1 Antibody (CAB20433)
- SKU:
- CAB20433
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- OBF
- Synonyms:
- IZUMO
Description
| Product Name: | IZUMO1 Rabbit pAb |
| Product Code: | CAB20433 |
| Size: | 50uL, 100uL |
| Synonyms: | OBF, IZUMO |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human IZUMO1 (NP_872381.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human IZUMO1 (NP_872381.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 284359 |
| Uniprot: | Q8IYV9 |
| Calculated MW: | 38kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | IZUMO1: Involved in the fertilization process. May be involved in the fusion of the sperm with the egg. Belongs to the Izumo family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: integral to membrane; plasma membrane Molecular Function:protein homodimerization activity; receptor binding Biological Process: cell adhesion; fusion of sperm to egg plasma membrane; single fertilization; sperm-egg recognition |
| NCBI Summary: | The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8IYV9 |
| NCBI GenInfo Identifier: | 296434545 |
| NCBI Gene ID: | 284359 |
| NCBI Accession: | Q8IYV9.2 |
| UniProt Secondary Accession: | Q8IYV9,Q6Q8P6, Q6Q8P7, |
| UniProt Related Accession: | Q8IYV9 |
| Molecular Weight: | 7,339 Da |
| NCBI Full Name: | Izumo sperm-egg fusion protein 1 |
| NCBI Synonym Full Names: | izumo sperm-egg fusion 1 |
| NCBI Official Symbol: | IZUMO1 |
| NCBI Official Synonym Symbols: | OBF; IZUMO |
| NCBI Protein Information: | izumo sperm-egg fusion protein 1 |
| UniProt Protein Name: | Izumo sperm-egg fusion protein 1 |
| UniProt Synonym Protein Names: | Oocyte binding/fusion factor; OBF; Sperm-specific protein izumo |
| Protein Family: | Izumo sperm-egg fusion protein |
| UniProt Gene Name: | IZUMO1 |
| UniProt Entry Name: | IZUM1_HUMAN |
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