Epigenetics & Nuclear Signaling Antibodies 3

Anti-IWS1 Antibody (CAB4839)

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SKU:
CAB4839

Description

Product Name:IWS1 Rabbit pAb
Product Code:CAB4839
Size:20uL, 50uL, 100uL
Synonyms:IWS1
Applications:IF
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 570-819 of human IWS1 (NP_060439.2).
Applications:IF
Recommended Dilutions:IF 1:50 - 1:200
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 570-819 of human IWS1 (NP_060439.2).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AAEE DRQL NNQK KPAL KKLT LLPA VVMH LKKQ DLKE TFID SGVM SAIK EWLS PLPD RSLP ALKI REEL LKIL QELP SVSQ ETLK HSGI GRAV MYLY KHPK ESRS NKDM AGKL INEW SRPI FGLT SNYK GMTR EERE QRDL EQMP QRRR MNST GGQT PRRD LEKV LTGE EKAL RPGD PGFC ARAR VPMP SNKD YVVR PKWN VEME SSRF QATS KKGI SRLD KQMR KFTD IRKK SRSA HAVK ISIE GNKM PL
Gene ID:55677
Uniprot:Q96ST2
Cellular Location:Nucleus
Calculated MW:41kDa/68kDa
UniProt Protein Function:IWS1: a Pol II transcription elongation factor essential for mammalian cell proliferation. Interacts with Spt6 and Spt5. Depletion of endogenous human IWS1 results in mRNA processing defects. Three alternatively spliced human isoforms have been described.
UniProt Protein Details:

Protein type:Transcription factor

Chromosomal Location of Human Ortholog: 2q14.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function:protein binding; DNA binding

Biological Process: mRNA transport; regulation of transcription, DNA-dependent; transcription, DNA-dependent; RNA splicing; mRNA processing; regulation of mRNA processing

UniProt Code:Q96ST2
NCBI GenInfo Identifier:85542184
NCBI Gene ID:55677
NCBI Accession:Q96ST2.2
UniProt Secondary Accession:Q96ST2,Q2TB65, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8
UniProt Related Accession:Q96ST2
Molecular Weight:819
NCBI Full Name:Protein IWS1 homolog
NCBI Synonym Full Names:IWS1 homolog (S. cerevisiae)
NCBI Official Symbol:IWS1  
NCBI Protein Information:protein IWS1 homolog; IWS1-like protein; interacts with Spt6
UniProt Protein Name:Protein IWS1 homolog
UniProt Synonym Protein Names:IWS1-like protein
Protein Family:IWS1-like protein
UniProt Gene Name:IWS1  
UniProt Entry Name:IWS1_HUMAN
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Additional Information

Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IWS1
Research Area:
Epigenetics and Nuclear Signaling
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