Immunology Antibodies 2
Anti-IVNS1ABP Antibody (CAB4442)
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- SKU:
- CAB4442
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- IVNS1ABP
- Synonyms:
- FLARA3
- Synonyms:
- HSPC068
- Synonyms:
- KLHL39
- Synonyms:
- ND1
- Synonyms:
- NS-1
- Synonyms:
- NS1-BP
- Synonyms:
- NS1BP
- Research Area:
- Immunology
Description
| Product Name: | IVNS1ABP Rabbit pAb |
| Product Code: | CAB4442 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | IVNS1ABP, FLARA3, HSPC068, KLHL39, ND1, NS-1, NS1-BP, NS1BP |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, Mouse kidney, Mouse lung, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MIPN GYLM FEDE NFIE SSVA KLNA LRKS GQFC DVRL QVCG HEML AHRA VLAC CSPY LFEI FNSD SDPH GISH VKFD DLNP EAVE VLLN YAYT AQLK ADKE LVKD VYSA AKKL KMDR VKQV CGDY LLSR MDVT SCIS YRNF ASCM GDSR LLNK VDAY IQEH LLQI SEEE EFLK LPRL KLEV MLED NVCL PSNG KLYT KVIN WVQR SIWE NGDS LEEL MEEV QTLY YSAD HKLL DGNL LDGQ AEVF GSDD DHIQ FVQK KPPR ENGH KQIS SSST GCLS SPNA TVQS PKHE WKIV ASEK TSNN |
| Gene ID: | 10625 |
| Uniprot: | Q9Y6Y0 |
| Cellular Location: | Cytoplasm, Nucleus, cytoskeleton, nucleoplasm |
| Calculated MW: | 71kDa |
| Observed MW: | 72kDa |
| UniProt Protein Function: | IVNS1ABP: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines. May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q25.1-q31.1 Cellular Component: nucleoplasm; spliceosome; transcription factor complex; cytoplasm; actin cytoskeleton Biological Process: transcription from RNA polymerase III promoter; viral reproduction; response to virus; RNA splicing |
| UniProt Code: | Q9Y6Y0 |
| NCBI GenInfo Identifier: | 146325015 |
| NCBI Gene ID: | 10625 |
| NCBI Accession: | Q9Y6Y0.3 |
| UniProt Secondary Accession: | Q9Y6Y0,Q1G4T6, Q1G4T7, Q5TF75, Q6NW38, Q7LCG2, Q9NZX0 Q9Y480, A8K8R6, |
| UniProt Related Accession: | Q9Y6Y0 |
| Molecular Weight: | 642 |
| NCBI Full Name: | Influenza virus NS1A-binding protein |
| NCBI Synonym Full Names: | influenza virus NS1A binding protein |
| NCBI Official Symbol: | IVNS1ABP |
| NCBI Official Synonym Symbols: | ND1; NS-1; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068 |
| NCBI Protein Information: | influenza virus NS1A-binding protein; NS1-binding protein; NCX downstream gene 1; kelch-like family member 39; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3 |
| UniProt Protein Name: | Influenza virus NS1A-binding protein |
| UniProt Synonym Protein Names: | Aryl hydrocarbon receptor-associated protein 3 |
| Protein Family: | Influenza virus NS1A-binding protein |
| UniProt Gene Name: | IVNS1ABP |
| UniProt Entry Name: | NS1BP_HUMAN |
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