Cell Biology Antibodies 11
Anti-ITLN1 Antibody (CAB7234)
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- SKU:
- CAB7234
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ITLN1 Antibody |
| Antibody SKU: | CAB7234 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-313 of human ITLN1 (NP_060095.2). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse heart, Rat intestine |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-313 of human ITLN1 (NP_060095.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TDEA NTYF KEWT CSSS PSLP RSCK EIKD ECPS AFDG LYFL RTEN GVIY QTFC DMTS GGGG WTLV ASVH ENDM RGKC TVGD RWSS QQGS KAVY PEGD GNWA NYNT FGSA EAAT SDDY KNPG YYDI QAKD LGIW HVPN KSPM QHWR NSSL LRYR TDTG FLQT LGHN LFGI YQKY PVKY GEGK CWTD NGPV IPVV YDFG DAQK TASY YSPY GQRE FTAG FVQF RVFN NERA ANAL CAGM RVTG CNTE HHCI GGGG YFPE ASPQ QCGD FSGF DWSG YGTH VGYS SSRE ITEA AVLL FYR |
| Gene ID: | 55600 |
| Uniprot: | Q8WWA0 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor, Secreted |
| Calculated MW: | 34kDa |
| Observed MW: | 37kDa |
| Synonyms: | ITLN1, HL-1, HL1, INTL, ITLN, LFR, hIntL, omentin |
| Background: |
| UniProt Protein Function: | ITLN1: Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism. |
| UniProt Protein Details: | Protein type:Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: brush border membrane; receptor complex; lipid raft Molecular Function:carbohydrate binding Biological Process: positive regulation of glucose import; response to nematode; positive regulation of protein amino acid phosphorylation |
| UniProt Code: | Q8WWA0 |
| NCBI GenInfo Identifier: | 55976553 |
| NCBI Gene ID: | 55600 |
| NCBI Accession: | Q8WWA0.1 |
| UniProt Secondary Accession: | Q8WWA0,Q5IWS4, Q5VYI4, Q6YDJ3, Q9NP67, |
| UniProt Related Accession: | Q8WWA0 |
| Molecular Weight: | 313 |
| NCBI Full Name: | Intelectin-1 |
| NCBI Synonym Full Names: | intelectin 1 (galactofuranose binding) |
| NCBI Official Symbol: | ITLN1 |
| NCBI Official Synonym Symbols: | HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin |
| NCBI Protein Information: | intelectin-1; ITLN-1; endothelial lectin HL-1; galactofuranose-binding lectin; intestinal lactoferrin receptor |
| UniProt Protein Name: | Intelectin-1 |
| UniProt Synonym Protein Names: | Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Omentin |
| Protein Family: | Intelectin |
| UniProt Gene Name: | ITLN1 |
| UniProt Entry Name: | ITLN1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ITLN1 antibody (CAB7234) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse intestin using ITLN1 Rabbit pAb (CAB7234) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of rat intestine using ITLN1 Rabbit pAb (CAB7234) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of mouse colon using ITLN1 Rabbit pAb (CAB7234) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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