Immunology Antibodies 1
Anti-ITK Antibody (CAB0566)
- SKU:
- CAB0566
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-ITK Antibody |
| Antibody SKU: | CAB0566 |
| Antibody Size: | 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human ITK |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse spleen |
| Immunogen: | A synthetic peptide of human ITK |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3702 |
| Uniprot: | Q08881 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 71kDa |
| Observed MW: | 70kDa |
| Synonyms: | ITK, EMT, LPFS1, LYK, PSCTK2 |
| Background: | This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. |
| UniProt Code: | Q08881 |
| NCBI GenInfo Identifier: | 585361 |
| NCBI Gene ID: | 3702 |
| NCBI Accession: | Q08881.1 |
| UniProt Secondary Accession: | Q08881,Q32ML7, B2R752, |
| UniProt Related Accession: | Q08881 |
| Molecular Weight: | 620 |
| NCBI Full Name: | Tyrosine-protein kinase ITK/TSK |
| NCBI Synonym Full Names: | IL2-inducible T-cell kinase |
| NCBI Official Symbol: | ITK |
| NCBI Official Synonym Symbols: | EMT; LYK; LPFS1; PSCTK2 |
| NCBI Protein Information: | tyrosine-protein kinase ITK/TSK; kinase EMT; T-cell-specific kinase; tyrosine-protein kinase LYK; IL-2-inducible T cell kinase; IL-2-inducible T-cell kinase; homolog of mouse T-cell itk/tsk; interleukin-2-inducible T cell kinase; interleukin-2-inducible T |
| UniProt Protein Name: | Tyrosine-protein kinase ITK/TSK |
| UniProt Synonym Protein Names: | Interleukin-2-inducible T-cell kinase; IL-2-inducible T-cell kinase; Kinase EMT; T-cell-specific kinase; Tyrosine-protein kinase Lyk |
| Protein Family: | Tyrosine-protein kinase |
| UniProt Gene Name: | ITK |
| UniProt Entry Name: | ITK_HUMAN |
 | Western blot analysis of extracts of mouse spleen, using ITK antibody (CAB0566). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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