Cell Biology Antibodies 11
Anti-ITGA9 Antibody (CAB7693)
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- SKU:
- CAB7693
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ITGA9 Antibody |
| Antibody SKU: | CAB7693 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-250 of human ITGA9 (NP_002198.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | mouse testis, mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-250 of human ITGA9 (NP_002198.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YNLD PQRP VHFQ GPAD SFFG YAVL EHFH DNTR WVLV GAPK ADSK YSPS VKSP GAVF KCRV HTNP DRRC TELD MARG KNRG TSCG KTCR EDRD DEWM GVSL ARQP KADG RVLA CAHR WKNI YYEA DHIL PHGF CYII PSNL QAKG RTLI PCYE EYKK KYGE EHGS CQAG IAGF FTEE LVVM GAPG SFYW AGTI KVLN LTDN TYLK LNDE VIMN RRYT YLGY A |
| Gene ID: | 3680 |
| Uniprot: | Q13797 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 114kDa |
| Observed MW: | 114kDa |
| Synonyms: | ITGA9, ALPHA-RLC, ITGA4L, RLC |
| Background: | This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. |
| UniProt Protein Function: | ITGA9: Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin. Belongs to the integrin alpha chain family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 3p21.3 Cellular Component: basal plasma membrane; plasma membrane; integrin complex Molecular Function:collagen binding; metal ion binding; laminin binding Biological Process: integrin-mediated signaling pathway; neutrophil chemotaxis; axon guidance; extracellular matrix organization and biogenesis; wound healing; cell adhesion |
| NCBI Summary: | This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13797 |
| NCBI GenInfo Identifier: | 229462922 |
| NCBI Gene ID: | 3680 |
| NCBI Accession: | Q13797.2 |
| UniProt Related Accession: | Q13797 |
| Molecular Weight: | |
| NCBI Full Name: | Integrin alpha-9 |
| NCBI Synonym Full Names: | integrin subunit alpha 9 |
| NCBI Official Symbol: | ITGA9 |
| NCBI Official Synonym Symbols: | RLC; ITGA4L; ALPHA-RLC |
| NCBI Protein Information: | integrin alpha-9 |
| UniProt Protein Name: | Integrin alpha-9 |
| UniProt Synonym Protein Names: | Integrin alpha-RLC |
| UniProt Gene Name: | ITGA9 |
| UniProt Entry Name: | ITA9_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ITGA9 antibody (CAB7693) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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