Cell Biology Antibodies 14
Anti-IRF2BP2 Antibody (CAB17985)
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- SKU:
- CAB17985
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-IRF2BP2 Antibody |
| Antibody SKU: | CAB17985 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human IRF2BP2. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | mouse spleen, mouse lung |
| Immunogen: | Recombinant protein of human IRF2BP2. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 359948 |
| Uniprot: | Q7Z5L9 |
| Cellular Location: | |
| Calculated MW: | 61kDa |
| Observed MW: | 61kDa |
 | Western blot - IRF2BP2 Polyclonal Antibody (CAB17985) |
| Synonyms: | IRF2BP2 |
| Background: |
| UniProt Protein Function: | IRF2BP2: Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle. Belongs to the IRF2BP family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 1q42.3 Cellular Component: nucleoplasm; cytoplasm; nucleus Molecular Function:metal ion binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q7Z5L9 |
| NCBI GenInfo Identifier: | 229462882 |
| NCBI Gene ID: | 359948 |
| NCBI Accession: | Q7Z5L9.2 |
| UniProt Secondary Accession: | Q7Z5L9,Q6P083, Q7Z5L8, Q8N351, Q8WUH8, B1AM35, B1AM36 |
| UniProt Related Accession: | Q7Z5L9 |
| Molecular Weight: | 587 |
| NCBI Full Name: | Interferon regulatory factor 2-binding protein 2 |
| NCBI Synonym Full Names: | interferon regulatory factor 2 binding protein 2 |
| NCBI Official Symbol: | IRF2BP2 |
| NCBI Protein Information: | interferon regulatory factor 2-binding protein 2; IRF-2-binding protein 2 |
| UniProt Protein Name: | Interferon regulatory factor 2-binding protein 2 |
| Protein Family: | Interferon regulatory factor 2-binding protein |
| UniProt Gene Name: | IRF2BP2 |
| UniProt Entry Name: | I2BP2_HUMAN |
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